Results 91 to 100 of about 663,172 (393)

Commutating brushes tested in dc motors in dry argon atmospheres [PDF]

open access: yes, 1970
Test apparatus, procedures, and results are given for dc-motor brushes operating in dry argon.
Bernstein, G. J.   +2 more
core   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

open access: yesMolecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Argon Abundances in the Solar Neighborhood: Non-LTE Analysis of Orion Association B-type Stars

open access: yes, 2008
Argon abundances have been derived for a sample of B main-sequence stars in the Orion association. The abundance calculations are based on NLTE metal line-blanketed model atmospheres calculated with the NLTE code TLUSTY and an updated and complete argon ...
Bennett W. R., Jr.   +12 more
core   +1 more source

The role of argon in stroke [PDF]

open access: yesMedical Gas Research, 2018
Stroke, also known as "cerebrovascular accident", is an acute cerebrovascular disease that is caused by a sudden rupture of blood vessels in the brain or obstruction of the blood supply by blockage of blood vessels, thus including hemorrhagic and ischemic strokes.
Jin-Quan Li   +4 more
openaire   +3 more sources

Spectroscopic Characterization of a Radio-Frequency Argon Plasma Jet Discharge in Ambient Air

open access: yes, 2015
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P. Cullen, V. Milosavljević
semanticscholar   +1 more source

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

open access: yesMolecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source

High Efficiency Detection of Argon Scintillation Light of 128nm Using LAAPDs

open access: yes, 2005
The possibility of efficient collection and detection of vacuum ultraviolet light as emitted by argon, krypton, and xenon gas is studied. Absolute quantum efficiencies of large area avalanche photodiodes (LAAPDs) are derived at these wavelengths.
Chandrasekharan, R.   +4 more
core   +2 more sources

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

Argon Inhalation Attenuates Retinal Apoptosis after Ischemia/Reperfusion Injury in a Time- and Dose-Dependent Manner in Rats

open access: yesPLoS ONE, 2014
Purpose Retinal ischemia and reperfusion injuries (IRI) permanently affect neuronal tissue and function by apoptosis and inflammation due to the limited regenerative potential of neurons.
Felix Ulbrich   +6 more
semanticscholar   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

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