Results 141 to 150 of about 227,128 (319)

No relevant pharmacokinetic interaction between the KRAS G12C inhibitor sotorasib and the direct oral anticoagulant rivaroxaban in healthy subjects

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Venous thromboembolism (VTE) is common in cancer patients, with direct oral anticoagulants, including rivaroxaban, recommended as first‐line therapy. However, oral anticoagulant use is limited due to the growing use of targeted therapy and concerns about drug‐drug interactions.
Esther M. Hollander   +7 more
wiley   +1 more source

Comparative Study of the use of Arithmetic Mean and Geometric Mean for Data Aggregation in FMEA Analysis

open access: yesCovenant Journal of Engineering Technology, 2017
Failure Mode and Effects Analysis (FMEA) is a commonly use approach for ranking risk of failure modes of most marine machinery system. However, the Risk Priority Number (RPN) use for evaluating risk within FMEA framework have several limitations and as ...
Ikuobase Emovon, Modestus Okechukwu Okwu
doaj  

Computational design of two‐dimensional MA2Z4 family field‐effect transistor for future Ångström‐scale CMOS technology nodes

open access: yesInfoMat, EarlyView.
Two‐dimensional MA2Z4 such as MoSi2N4 offer a new path to extend transistor scaling beyond the limits of silicon. Due to their exceptional properties, these 2D semiconductors are promising candidates for future Ångström‐scale CMOS technology. This review outlines the computational design and roadmap bridging materials discovery, device design and ...
Che Chen Tho   +11 more
wiley   +1 more source

Navigating the Uncertainty: Unveiling the Impact of Trade Policy Uncertainty on GVC Ascent in Chinese Listed Companies

open access: yesInternational Studies of Economics, EarlyView.
ABSTRACT This study is based on real options theory and uses a sample of Chinese listed companies from 2000 to 2016 to investigate the dynamic process and mechanisms by which trade policy uncertainty affects the upgrading of enterprises within the global value chain (GVC). The article finds that trade policy uncertainty has a positive forcing effect on
Shiyi Wu, Rui Niu
wiley   +1 more source

On approximating the arithmetic-geometric mean and complete elliptic integral of the first kind

open access: yesJournal of Mathematical Analysis and Applications, 2018
Zhen-Hang Yang   +3 more
semanticscholar   +1 more source

Evaluating the Endocrine‐Disrupting and Oxidative Stress Potential of a 50‐Component Human‐Relevant Complex Chemical Mixture Using In Vitro Tests

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Humans are chronically exposed to mixtures of environmental contaminants. Exposure to endocrine‐disrupting chemicals (EDCs) contributes to increased health impairment observed globally. This study aimed to evaluate the endocrine‐disruptive and oxidative stress potential of a human‐relevant, complex chemical mixture in vitro.
Josefin Engelhardt   +5 more
wiley   +1 more source

Probiotic fermentation of soybeans and use of fermented soy in cookies

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND With increasing prevalence of mental health issues such as insomnia and anxiety, γ‐aminobutyric acid (GABA) has gained attention for its neurological benefits. The development of GABA‐rich functional foods has emerged as a promising research direction. Soybeans, rich in glutamate, are excellent substrates for GABA biosynthesis using
Xin Chen   +3 more
wiley   +1 more source

Medial‐pivot design total knee arthroplasty provides higher post‐operative patient satisfaction than posterior‐stabilized design under mechanical alignment

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Numerous studies have compared post‐operative patient‐reported outcome measures (PROMs) between medial‐pivot design total knee arthroplasty (MP‐TKA) and posterior‐stabilized design TKA (PS‐TKA); however, whether MP‐TKA demonstrates superior outcomes remains controversial.
Sho Masuda   +5 more
wiley   +1 more source

Impact of E‐Beam Sterilization on Bioglass Composite Shape Memory Scaffolds

open access: yesMacromolecular Materials and Engineering, EarlyView.
Electron beam (E‐beam) sterilization is an attractive alternative to conventional methods (e.g., ethylene oxide) to sterilize medical devices such as scaffolds used to heal bone defects. Herein, the impact of E‐beam sterilization on the properties of “self‐fitting” shape memory polymer (SMP) scaffolds prepared from resorbable polyesters and a bioglass ...
Brandon M. Nitschke   +2 more
wiley   +1 more source

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