Results 191 to 200 of about 174,174 (316)

Safety, tolerability, pharmacokinetics and pharmacodynamics of HSK31858, a novel oral dipeptidyl peptidase‐1 inhibitor, in healthy volunteers: An integrated phase 1, randomized, double‐blind, placebo‐controlled, single‐ and multiple‐ascending dose study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Dipeptidyl peptidase‐1 (DPP‐1) inhibitors have been studied for the treatment of neutrophil‐mediated inflammatory diseases including bronchiectasis, bronchial asthma and cystic fibrosis. This study evaluated the pharmacokinetics, pharmacodynamics, safety and tolerability of DPP‐1 inhibitor HSK31858 in healthy Chinese volunteers.
Yuhao Wang   +7 more
wiley   +1 more source

Pedagogical considerations in the automation era: A systematic literature review of AIEd in K‐12 authentic settings

open access: yesBritish Educational Research Journal, EarlyView.
Abstract The introduction of artificial intelligence (AI) into education holds promise for supporting and augmenting teaching and learning‐related activities. Yet, despite its potential, there is limited empirical research on the use of AI in K‐12 settings exploring the pedagogical grounding, impact and implications of the technological solutions.
Paraskevi Topali   +3 more
wiley   +1 more source

THE EFFECT OF MENTAL ARITHMETIC ON CEREBRAL CIRCULATION AND METABOLISM 1

open access: bronze, 1955
Louis Sokoloff   +4 more
openalex   +1 more source

A Romantic Genius? The Experience of Knowledge that Shaped Werner Heisenberg's Scientific Persona

open access: yesBerichte zur Wissenschaftsgeschichte, EarlyView.
In 1976, the year that Werner Heisenberg passed away, Armin Hermann published a short biography, titled Werner Heisenberg in Selbstzeugnissen und Bilddokumenten. Since then, historians and biographers have offered their accounts on Heisenberg's life and his contributions to modern physics. Many of these biographies present Heisenberg as a genius.
Elena Schaa
wiley   +1 more source

Scalable, High‐Density Expansion of Human Mesenchymal Stem Cells on Microcarriers Using the Bach Impeller in Stirred‐Tank Reactors

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT This paper describes the results of process developmental experiments to achieve higher cell densities in the manufacturing of hMSCs using the novel Bach impeller in a stirred‐tank bioreactor. Engineering experiments have previously shown that the Bach impeller represents an efficient mixing device that suspends particles in fluids at low ...
Tom A. Wyrobnik   +5 more
wiley   +1 more source

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