Review of Transcriptomic Biomarkers That Predict In Vitro Genotoxicity in Human Cell Lines
ABSTRACT The current genotoxicity testing paradigm provides little mechanistic information, has poor specificity in predicting carcinogenicity in humans, and is not suited to assessing a large number of chemicals. Genomic technologies enable the characterization of genome‐wide transcriptional changes in response to chemical treatments that can inform ...
Heng‐Hong Li+7 more
wiley +1 more source
Wearable Wireless Functional Near-Infrared Spectroscopy System for Cognitive Activity Monitoring. [PDF]
Victorio M+5 more
europepmc +1 more source
Fast Proxy Centers for the Jeffreys Centroid: The Jeffreys-Fisher-Rao Center and the Gauss-Bregman Inductive Center. [PDF]
Nielsen F.
europepmc +1 more source
Exploring Low‐Global Warming Potential Refrigerants for Medium‐Charge Systems
This study evaluates 15 low‐global warming potential (GWP) refrigerants as alternatives for medium‐charge systems, focusing on environmental impacts, operational performance, and system design integration. Key findings reveal R‐447A's suitability for standard climates and R‐454B's advantages in high ambient conditions, providing actionable guidance for
Fadi Alsouda+3 more
wiley +1 more source
On-demand tailoring soliton patterns through intracavity spectral phase programming. [PDF]
Zhang H+9 more
europepmc +1 more source
Abstract Uncertainty is a critical factor that can hinder the quality and potential applications of life cycle assessment (LCA) results. A prominent source of uncertainty stems from the life cycle inventory (LCI) data. Various methodologies exist to estimate the uncertainty associated with LCI data, primarily based on the widely used structured ...
Eric C. D. Tan+5 more
wiley +1 more source
Respiratory Function of Fontan Pediatric Patients with Hypoplastic Left Heart Syndrome and Other Morphologies of Functionally Single Ventricle-A Pilot Study. [PDF]
Kocot K+4 more
europepmc +1 more source
A consensus model in legislative decision‐making: The council of the European Union
Abstract The culture of consensus influences legislative decision‐making within the Council of the European Union, often leading to broad coalitions in which even the preferences of isolated member states are considered. Nevertheless, despite its significance, this culture has been insufficiently studied through formal models predicting EU legislative ...
Arash Pourebrahimi
wiley +1 more source
Pharmacokinetics, Pharmacodynamic, Safety and Tolerability of Fazamorexant, a Novel Dual Orexin Receptor Antagonist: Report of the First-in-Human Study. [PDF]
Ni J+6 more
europepmc +1 more source
Abstract Increasingly, it has been recognized that non‐seizure‐related factors influence how people with epilepsy perform on neuropsychological tests. Therefore, neuropsychologists need to recognize the constellation of factors that can contribute to the neurocognitive presentation of a person with epilepsy and consider these factors in the ...
Mary Lou Smith+12 more
wiley +1 more source