Results 151 to 160 of about 161,552 (257)

Ecosystem retrogression enhances cross‐domain microbial stability and increases the genetic potential for nutrient cycling

mLife, EarlyView.
Abstract Ecosystem retrogression drives nutrient depletion, reduced productivity, and profound reorganization of soil microbial communities. Using amplicon sequencing and genome‐resolved metagenomics, we examined how cross‐domain microbial networks and functional gene potential respond to long‐term phosphorus and nitrogen limitation along the well ...
Javier A. Ceja‐Navarro, Dishant Patel, Garret Genco, Alyssa Byer, Daliang Ning, Kenneth H. Wan, Susan E. Celniker, Jizhong Zhou, Paul Dijkstra, Bruce A. Hungate, Jennifer Pett‐Ridge, Eoin L. Brodie   +11 more
wiley   +1 more source

Artificial intelligence for detection and staging of Alzheimer's disease using retinal images. [PDF]

Cochrane Database Syst Rev
Panjwani M, Holmes JM, Liu SH, Lee E, Rapcsak S, Harris A, Kozak I.   +6 more
europepmc   +1 more source

Enabling Functional Independence: A Scoping Review of Upper Extremity Assistive Devices for Adults With Progressive Neuromuscular Diseases

Muscle &Nerve, EarlyView.
This scoping review summarizes the spectrum of upper extremity assistive devices for adults with progressive neuromuscular diseases, ranging from low‐tech supports to advanced robotics, exoskeletons, and brain‐computer interface systems. While these technologies show promise for improving enabling function, current evidence is largely limited to ...
Katherine M. Burke, Stephanie Johnson, Kayla Chomko, Angela Escalante, Kendall C. Hall, Melis Lydston, Courtney Uek, Gabriella Casagrande, Hyun Jung Kim, James Arnold, David Pont‐Esteban, Harrison Young, Conor Walsh, Sabrina Paganoni   +13 more
wiley   +1 more source

Severe Cryptosporidiosis Following Tumor-Infiltrating Lymphocyte Therapy in a Patient With Metastatic Mucosal Melanoma. [PDF]

ACG Case Rep J
Gill G, Saab O, Patel K, Bhattacharyya AK, Roden D, Aggarwal A.   +5 more
europepmc   +1 more source

The Uncharted Territory of the New Obesity Drugs in Users Without Obesity: A Sociomedical Perspective

Obesity, EarlyView.
ABSTRACT The off‐label use of glucagon‐like peptide‐1 receptor agonists (GLP‐1ra) among people without obesity and/or diabetes is rapidly expanding, despite a lack of clinical justification or safety data in this population. This Perspective explores the sociomedical dimensions of this trend, highlighting key research gaps and emerging hypotheses ...
Fernanda Baeza Scagliusi, Bruno Gualano, Pernille Andreassen, Cindi SturtzSreetharan, Sissel Due Jensen, Alexandra Brewis   +5 more
wiley   +1 more source

Oral GLP‐1RA TERN‐601 for Adults With Obesity/Overweight: Placebo‐Controlled, Multiple‐Ascending‐Dose, Phase 1 and 2 Studies

Obesity, EarlyView.
ABSTRACT Objective The safety, tolerability, pharmacokinetics, and efficacy of TERN‐601, a once‐daily, oral small‐molecule glucagon‐like peptide‐1 (GLP‐1) receptor agonist, were studied in Phase 1 and 2 clinical studies. Methods The Phase 1 (28‐day) and Phase 2 (12‐week), randomized, double‐blind, placebo‐controlled, multiple‐ascending‐dose studies ...
W. Timothy Garvey, Julio Rosenstock, Harold E. Bays, Douglas Denham, Anita Kohli, Melanie Haines, Christopher Jones, Ellen Kwan, Erin Castelloe, Tonya Marmon, Emil Kuriakose, Cara Nelson   +11 more
wiley   +1 more source

Exploring Perspectives on a Women in Medicine and Science Mentorship and Networking Event: A Pilot Quality Improvement Initiative at the University of Arizona College of Medicine-Tucson. [PDF]

Cureus
Hesselbach A, Shrourou F, Molzahn A, Parikh T.   +3 more
europepmc   +1 more source

Nonstationarity in wildlife disease dynamics: insights from the prairie dog–plague system

Oikos, EarlyView.
Ecological relationships often vary in strength and direction across ecosystems, a pattern that has become increasingly evident as ecology expands to broader spatial and temporal scales. Although such nonstationarity – the changing effect of predictor variables across spatiotemporal contexts – is widely acknowledged in ecological research, it has ...
Gabriel M. Barrile, Joshua F. Layfield, David J. Augustine, Lauren M. Porensky, Courtney J. Duchardt, Imtiaz Rangwala, Ana D. Davidson   +6 more
wiley   +1 more source

Biophysical membrane responses of hypoxic prostate cancer cells depend on kindlin-2. [PDF]

Biophys J
Hernandez-Cortes D, Gard JMC, Ryniawec JM, Seppanen NK, Nelson CS, Harryman WL, Warfel NA, Rogers GC, Sayyid R, Cress AE.   +9 more
europepmc   +1 more source

Using a social‐ecological macrosystems framework to understand how human activities alter ecological synchrony

People and Nature, EarlyView.
Abstract Different aspects of ecological systems, biotic or abiotic, often fluctuate in coordinated patterns over space and time. Such high concordance between ecological processes is often referred to as ecological synchrony. Human activities, including and beyond climate change, have the potential to alter ecological synchrony by disrupting or ...
Yiluan Song, Mallory Barnes, K. Ann Bybee‐Finley, Kyla M. Dahlin, Travis McDevitt‐Galles, Stephan B. Munch, Guillermo E. Ponce‐Campos, Casey Youngflesh, Benjamin Zuckerberg, Kai Zhu   +9 more
wiley   +1 more source