Results 31 to 40 of about 17,211 (243)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

ZER1 Restrains Pressure Overload‐Induced Cardiac Remodeling by Targeting DVL2 for Gly/N‐Degron‐Dependent Degradation

open access: yesAdvanced Science, EarlyView.
Pressure overload suppresses cardiomyocyte ZER1, weakening CRL2Zer1‐mediated DVL2 degradation and allowing DVL2 accumulation. Elevated DVL2 activates CaMKII‐HDAC4‐MEF2C signaling, drives fetal gene reactivation, and promotes pathological remodeling.
Mingchao Jiang   +27 more
wiley   +1 more source

Del mito a la conservación del armadillo en la región otomí-mazahua

open access: yesAnales de Antropología, 2023
Los pueblos otomí-mazahua que habitan en el Estado de México mantienen un vínculo con su entorno natural que va más allá de la división entre humanos y animales; esta relación interespecie nos permite entender cómo en el pensamiento indígena, la vida ...
David Gómez Sánchez   +2 more
doaj   +1 more source

35 Individuals With HUWE1‐Related Neurodevelopmental Disorder and Suggested Clinical Evaluations

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT HUWE1 (HECT, UBA, and WWE Domain Containing E3 Ubiquitin Protein Ligase1, OMIM 300697), located at Xp11.22, encodes a ubiquitin ligase that is highly conserved across species. Genetic variants in HUWE1 described in multiple independent studies cause X‐linked intellectual disability, including in the patients identified by Juberg, Marsidi, and ...
Mindy H. Li   +25 more
wiley   +1 more source

Ontogeny of murine bony semicircular canal form

open access: yesThe Anatomical Record, EarlyView.
Abstract The labyrinthine geometry and functional anatomy of the semicircular canals have intrigued scientists for decades, and there has been considerable interest in understanding how these complex structures grow and develop with evidence emerging from human studies that size maturation occurs exceptionally early by comparison with other systems ...
Marcela Cárdenas‐Serna   +1 more
wiley   +1 more source

Current Distribution of the Nine-Banded Armadillo (Dasypus novemcinctus) in the United States

open access: yesDiversity
The nine-banded armadillo (Dasypus novemcinctus: hereafter armadillo) was first recorded in the United States (U.S.) in the state of Texas in 1849 and has been expanding its range northward and eastward since then.
Brett A. DeGregorio, Anant Deshwal
doaj   +1 more source

Autochthonous Leprosy without Armadillo Exposure, Eastern United States

open access: yesEmerging Infectious Diseases, 2017
Autochthonous leprosy has been reported in New York City, where there are no wild armadillos. Recent autochthonous cases also have been reported in Georgia and Florida and blamed on armadillos, including cases with no known armadillo exposure ...
Tina Rendini, William Levis
doaj   +1 more source

Occupancy and Activity Patterns of Nine-Banded Armadillos (Dasypus novemcinctus) in a Suburban Environment

open access: yesDiversity, 2023
The geographic range of the nine-banded armadillo (Dasypus novemcinctus) has rapidly been expanding within the United States for the last 150 years. One of the factors contributing to this astounding range expansion is the species’ ability to survive in ...
Brett A. DeGregorio   +2 more
doaj   +1 more source

From armadillos to sloths: Patterns and variations in xenarthran coronary anatomy

open access: yesThe Anatomical Record, EarlyView.
Abstract Species of the superorder Xenarthra play a vital ecological role in the Neotropics. Despite their evolutionary significance, anatomical studies on their coronary circulation remain scarce. This study investigated the coronary anatomy of 82 hearts from nine Xenarthra species across the Dasypodidae, Myrmecophagidae, and Bradypodidae.
Wilson Viotto‐Souza   +5 more
wiley   +1 more source

How elephants beat cancer

open access: yeseLife, 2016
Elephants have significantly reduced their risk of cancer by duplicating an important gene called TP53.
Stephen J Gaughran   +2 more
doaj   +1 more source

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