Results 31 to 40 of about 13,322 (217)

ZER1 Restrains Pressure Overload‐Induced Cardiac Remodeling by Targeting DVL2 for Gly/N‐Degron‐Dependent Degradation

open access: yesAdvanced Science, EarlyView.
Pressure overload suppresses cardiomyocyte ZER1, weakening CRL2Zer1‐mediated DVL2 degradation and allowing DVL2 accumulation. Elevated DVL2 activates CaMKII‐HDAC4‐MEF2C signaling, drives fetal gene reactivation, and promotes pathological remodeling.
Mingchao Jiang   +27 more
wiley   +1 more source

Autochthonous Leprosy without Armadillo Exposure, Eastern United States

open access: yesEmerging Infectious Diseases, 2017
Autochthonous leprosy has been reported in New York City, where there are no wild armadillos. Recent autochthonous cases also have been reported in Georgia and Florida and blamed on armadillos, including cases with no known armadillo exposure ...
Tina Rendini, William Levis
doaj   +1 more source

Del mito a la conservación del armadillo en la región otomí-mazahua

open access: yesAnales de Antropología, 2023
Los pueblos otomí-mazahua que habitan en el Estado de México mantienen un vínculo con su entorno natural que va más allá de la división entre humanos y animales; esta relación interespecie nos permite entender cómo en el pensamiento indígena, la vida ...
David Gómez Sánchez   +2 more
doaj   +1 more source

Miro1 Protects Against Acute Kidney Injury Through Modulating Mitochondrial Homeostasis via Interaction With Sirt6

open access: yesAdvanced Science, EarlyView.
Ischemia‐reperfusion reduces Sirt6 activity, thereby increasing Miro1 acetylation. Hyperacetylated Miro1 exhibits perinuclear distribution and degradation, thereby inducing mitochondrial dysfunction and promoting apoptosis in renal tubular epithelial cells. This pathway reveals a mechanistic link between Sirt6‐mediated deacetylation and Miro1 stability
Lin Wu   +12 more
wiley   +1 more source

Ultrastructure and morphometry of ovarian follicles in the armadillo Chaetophractus villosus (Mammalia, Dasypodidae)

open access: yesBrazilian Journal of Biology
Ultrastructural and morphometric changes in oocyte and surrounding granulosa cells during armadillo follicular growth are described. Primordial, intermediary, early and late primary, secondary, tertiary and preovulatory Graafian follicles were found ...
S. M. CODÓN   +3 more
doaj   +1 more source

How elephants beat cancer

open access: yeseLife, 2016
Elephants have significantly reduced their risk of cancer by duplicating an important gene called TP53.
Stephen J Gaughran   +2 more
doaj   +1 more source

Occupancy and Activity Patterns of Nine-Banded Armadillos (Dasypus novemcinctus) in a Suburban Environment

open access: yesDiversity, 2023
The geographic range of the nine-banded armadillo (Dasypus novemcinctus) has rapidly been expanding within the United States for the last 150 years. One of the factors contributing to this astounding range expansion is the species’ ability to survive in ...
Brett A. DeGregorio   +2 more
doaj   +1 more source

Ontogeny of murine bony semicircular canal form

open access: yesThe Anatomical Record, EarlyView.
Abstract The labyrinthine geometry and functional anatomy of the semicircular canals have intrigued scientists for decades, and there has been considerable interest in understanding how these complex structures grow and develop with evidence emerging from human studies that size maturation occurs exceptionally early by comparison with other systems ...
Marcela Cárdenas‐Serna   +1 more
wiley   +1 more source

Expansion and Function of Repeat Domain Proteins During Stress and Development in Plants

open access: yesFrontiers in Plant Science, 2016
The recurrent repeats having conserved stretches of amino acids exists across all domains of life. Subsequent repetition of single sequence motif and the number and length of the minimal repeating motifs are essential characteristics innate to these ...
Manisha eSharma, GIRDHAR KUMAR PANDEY
doaj   +1 more source

Humans are not unique: difficult birth is common in placental mammals

open access: yesBiological Reviews, EarlyView.
ABSTRACT Human childbirth is widely presumed to be uniquely difficult and dangerous compared to birth in other mammals. Tight fetopelvic proportions can result in obstructed labour and contribute to high rates of maternal and neonatal mortality. Ideas summarised under the ‘obstetrical dilemma’ have contributed to this assumption by explaining difficult
Nicole D. S. Grunstra
wiley   +1 more source

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