Results 151 to 160 of about 56,011 (338)

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Operational and Material Causes of High-Pressure Turbine Disc Damage in the RD-33 Engine. [PDF]

Materials (Basel), 2023
Jóźwiak S, Kozakiewicz A, Kachel S, Zasada D.   +3 more
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Wartime Price Control and the Problem of Inflation [PDF]

, 1942
Clark, J. M.
core   +2 more sources

"Supplier Networks and Aircraft Production in Wartime Japan" [PDF]

The Japanese aircraft industry, which operated on a very small scale before World War II, became Japan's largest manufacturing industry by the end of the war. In this paper, we explore the causes of the growth of the aircraft industry during this time by
Tetsuji Okazaki
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Two new species of <i>Nitocrella</i> (Copepoda, Harpacticoida) from a spring in Loei Province, northeastern Thailand. [PDF]

Zookeys
Boonyanusith C, Brancelj A, Sanoamuang L.   +2 more
europepmc   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Sipadantoniusroihani gen. et sp. nov., a new genus and species of Pseudocyclopidae Giesbrecht, 1893 (Copepoda, Calanoida) from the marine cave "Turtle Tomb" of Sipadan Island, Sabah, Malaysia. [PDF]

Zookeys
Boonyanusith C, Wongkamhaeng K, Azman AR.   +2 more
europepmc   +1 more source

Unexpected thoracic injury caused by a falling bullet in a metropolis. [PDF]

Afr J Paediatr Surg, 2023
Akman M.
europepmc   +1 more source