Results 161 to 170 of about 56,011 (338)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Effect of unmanned aerial vehicle mission difficulty level on pilot's autonomic nervous system. [PDF]

Int J Occup Med Environ Health
Wojciechowski P, Wojtowicz K, Błaszczyk J.   +2 more
europepmc   +1 more source

Defence conversion - the disposal and demilitarization of heavy weapon systems (Edition 2) [PDF]

, 2007
-
core  

Changes in the French Defence Innovation System: New roles and capabilities for the Government Agency for Defence. [PDF]

Defence innovation systems are structured around two main groups of players that interact in the development of complex programmes: the state (the client and the government agency) and the systems integrators.
Lazaric, Nathalie, Mérindol, Valérie, Rochhia, Sylvie   +2 more
core  

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Effect of Elevated Temperature on Load-Bearing Capacity and Fatigue Life of Bolted Joints in CFRP Components. [PDF]

Polymers (Basel)
Arkuszyńska A, Rośkowicz M.
europepmc   +1 more source

Thermal Diffusivity Characteristics of the IN718 Alloy Tested with the Modified Pulse Method. [PDF]

Materials (Basel), 2022
Terpiłowski J, Jóźwiak S, Woroniak G, Szczepaniak R.   +3 more
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Connaught Battery and the Defence of the Atlantic Coast, 1906-1941 [PDF]

, 2015
Bruce Ellis, Roger Sarty
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source