Results 51 to 60 of about 510,131 (357)
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Armed Conflict in Mozambique in 2013
Politikon, 2015 In the context of an investment boom in the extractive sector, Mozambique recently experienced another armed conflict. The correlation between natural resources abundance and dependence and violent conflict is widely known as ‘resource curse’.
Cornelia Körtl
doaj +1 more source
Book Review: Rape loot pillage: the political economy of sexual violence in armed conflict. By Sara Meger. New York: Oxford University Press [PDF]
, 2018 Review of Rape loot pillage: the political economy of sexual violence in armed conflict. By Sara Meger. New York: Oxford University PressIn Rape loot pillage, Sara Meger offers a feminist political economy perspective on sexual violence in conflict ...
Aroussi, Sahla
core +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
The Gains From Trade: South American Economic Integration and the Resolution of Conflict [PDF]
, 2010 It has long been argued that expanding commercial relations between countries acts as an incentive for countries to avoid hostilities up to and including armed conflict.
Jake Johnston, Mark Weisbrot
core
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Organized Armed Groups in a non-International Conflict and International Humanitarian Law
International Review of Law, 2021 Non-International armed conflicts in which different armed groups are involved is the dominant feature of contemporary armed conflicts. Considering the complex and changing alliances of these groups and the extension of their hostilities across borders ...
إيمان حمدان
doaj +2 more sources
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
The Metamorphosis of the Defense Industry [PDF]
, 2002 The downsizing of the United States defense industry in recent years had a multitude of effects on defense and defense-related manufacturers. Besides the inevitable loss of jobs, these firms essentially had to reinvent themselves in order to compete in ...
Noble, Margaret A.
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source