Results 71 to 80 of about 457,788 (310)

Forecasting Change in Conflict Fatalities with Dynamic Elastic Net [PDF]

open access: yesarXiv, 2022
This article illustrates an approach to forecasting change in conflict fatalities designed to address the complexity of the drivers and processes of armed conflicts. The design of this approach is based on two main choices. First, to account for the specificity of conflict drivers and processes over time and space, we model conflicts in each individual
arxiv  

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

Mathematical models of intergroup conflicts [PDF]

open access: yesCompt. rend Acad. sci. Bulg. vol. 61, 993-1002 (2008), 2008
The human society today is far from perfection and conflicts between groups of humans are frequent events. One example for such conflicts are armed intergroup conflicts. The collective behavior of the large number of cooperating participants in these conflicts allows us to describe the conflict on the basis of models containing only few variables.
arxiv  

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald   +18 more
wiley   +1 more source

Basis of theoretical determination of armed conflict [PDF]

open access: yesВојно дело, 2017
This paper presents the theoretical basis of the origin and development of thoughts of armed conflict. The historical-comparative method, content analysis and the methods of definition and classification have been primarily applied in the paper.
Petrović Ivan   +2 more
doaj   +1 more source

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

open access: yesFEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa   +13 more
wiley   +1 more source

The Gains From Trade: South American Economic Integration and the Resolution of Conflict [PDF]

open access: yes, 2010
It has long been argued that expanding commercial relations between countries acts as an incentive for countries to avoid hostilities up to and including armed conflict.
Jake Johnston, Mark Weisbrot
core  

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

open access: yesAging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal   +8 more
wiley   +1 more source

The Metamorphosis of the Defense Industry [PDF]

open access: yes, 2002
The downsizing of the United States defense industry in recent years had a multitude of effects on defense and defense-related manufacturers. Besides the inevitable loss of jobs, these firms essentially had to reinvent themselves in order to compete in ...
Noble, Margaret A.
core   +1 more source

The neglected aspect of women and armed conflict - progressive development of the law [PDF]

open access: yes, 2005
© 2005 T.M.C. Asser Instituut and ContributorsThe impact of armed conflict on women is the subject of three recent international studies, two under the auspices of the United Nations and one undertaken by the International Committee of the Red Cross ...
Gardam, J.
core   +1 more source

Home - About - Disclaimer - Privacy