Results 81 to 90 of about 2,205,764 (331)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Improved Correlation Filter Tracking with Enhanced Features and Adaptive Kalman Filter
Sensors, 2019 In the field of visual tracking, discriminative correlation filter (DCF)-based trackers have made remarkable achievements with their high computational efficiency.
Hao Yang, Yingqing Huang, Zhihong Xie
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Study on the damage prediction model of PTFE/AL projectiles on the basis of regression analysis
AIP AdvancesPolytetrafluoroethylene/aluminum (PTFE/AL) projectiles can effectively enhance the damage efficiency of traditional projectiles. Numerical simulation via ANSYS AUTODYN and data analysis via Origin are effective means to help predict the damage efficiency
Huan Tong +4 more
doaj +1 more source
The relationships between explosive power for arms and legs and some biokinematic variables for team handball players [PDF]
مجلة الرافدين للعلوم الرياضية, 2007 Explosive power one of the most important physical element fitness in team handball, there are two basic important factors which are very effective in shooting these factor are explosive power for arms and legs and throwing velocity.
Mohammed .Khleel
doaj +1 more source
Constant lift rotor for a heavier than air craft [PDF]
, 1979 A rotor blade extended radially from a hub, characterized by an elongated spar and a plurality of axially aligned shells pivotally mounted on the spar is presented.
Stroub, R. H.
core +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
HAND, 2014 Both patients and providers hope for better management strategies for nonspecific activity-related upper limb pain (herein referred to as “arm ache”). The next innovation in the care of arm ache may arise from the strong evidence that mood, coping strategies (e.g., catastrophic thinking), and heightened illness concern—all very responsive to treatment
Hosein Ahmadzadeh, Chabok, David, Ring
openaire +2 more sources
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Biology of the Cell, 2010 Fusion proteins containing the FG/GLFG repeats of Nup98 joined to a homeodomain are implicated in leukemias. We find expression of these proteins leads to mislocalization of endogenous intranuclear Nup98.
Songli Xu, Maureen A. Powers
semanticscholar +1 more source