Results 81 to 90 of about 1,137 (216)

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Reaching Excellence

Acta Periodica Duellatorum, 2019
The sixteenth-century Collectanea of the condottiero Pietro Monte contains some of the most thorough writings that exist pertaining to the use of staff weapons.
Jacob Henry Deacon, Iason-Eleftherios Tzouriadis   +1 more
doaj  

Jason’s cloak in Apollonius Argonautica

Karanos
Jason’s shining arrival at Myrine, in Apollonius’ Argonautica, wearing a purple cloak and with a spear in the hand, highlights a glamorous heroic excellence that has its origin in Alexander the Great and evokes the military ceremonial mantles displayed ...
Alexandra Sousa
doaj   +1 more source

Does the fit of personal protective equipment affect functional performance? A systematic review across occupational domains. [PDF]

PLoS One, 2022
Brisbine BR, Radcliffe CR, Jones MLH, Stirling L, Coltman CE.   +4 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

The Gdańsk Landsknechts in the second half of the 16th century and their arms and armour

Fasciculi Archaeologiae Historicae, 2000
...
Marek Plewczyński
doaj  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Sex, military occupation and rank are associated with risk of anterior cruciate ligament injury in tactical-athletes. [PDF]

BMJ Mil Health, 2023
Aguero AD, Irrgang JJ, MacGregor AJ, Rothenberger SD, Hart JM, Fraser JJ.   +5 more
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

A Targeted Approach to Improve Asthma Control Using Community Pharmacists. [PDF]

Front Pharmacol, 2021
Serhal S, Saini B, Bosnic-Anticevich S, Krass I, Emmerton L, Bereznicki B, Bereznicki L, Mitchell B, Wilson F, Wright B, Wilson K, Weier N, Segrott R, Cleveland R, Jan S, Shan S, Billot L, Armour C.   +17 more
europepmc   +1 more source