Results 41 to 50 of about 937,801 (293)
A billion years arms-race between viruses, virophages, and eukaryotes
eLife, 2023 Bamfordviruses are arguably the most diverse group of viruses infecting eukaryotes. They include the Nucleocytoplasmic Large DNA viruses (NCLDVs), virophages, adenoviruses, Mavericks and Polinton-like viruses.
Jose Gabriel Nino Barreat +1 more
doaj +1 more source
Public communication of research universities ‘arms race’ for visibility or science substance?
, 2022 This book analyses communication of university research institutes, with a focus on science communication. Advancing the ‘decentralisation hypothesis’, it asserts that communication structures are increasingly built also at ‘subordinate unit’ levels of ...
core +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Deterrence and Arms Control: An Interview with Robert Gallucci
Journal for Peace and Nuclear Disarmament, 2021 Ambassador Robert Gallucci is Distinguished Professor in the Practice of Diplomacy at the Edmund A. Walsh School of Foreign Service, Georgetown University, where he earlier served as the Dean. He led the John D. and Catherine T.
Sharon Squassoni
doaj +1 more source
HYPERSONIC WEAPON SYSTEMS – A NEW WAVE OF ARMS RACE IN THE INDIAN OCEAN REGION
Margalla Papers, 2023 Technological advancements and tactical applications have always played a significant role in determining the outcomes of military conflicts. The emergence of Hypersonic Weapon Systems is considered a game-changer in contemporary and future warfare, as ...
Imran Raza, Nasir Mehmood
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Fears of a new nuclear arms race are wildly overblown [PDF]
, 2015 First paragraph: Many in the West suddenly seem to think we’re on the road to a new Cold War. Talk of a return to the era of nuclear rivalry swirls around Russia’s muscular and belligerent grandstanding over Ukraine, and the conflict has ...
Nehring, Holger
core
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Aging and Cancer, EarlyView.Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi +3 more
wiley +1 more source
Determining Military Expenditures: Arms Races and Spill-Over Effects in Cross-Section and Panel Data [PDF]
This paper considers the determinants of military spending, building on an emerging literature that estimates military expenditure demand functions in cross-section and panel data, incorporating ‘arms-race’ type effects.
Sam Perlo-Freeman +2 more
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THE DYNAMICS OF ONE ARMS RACE MATHEMATICAL MODEL WITH DELAY
Міжнародний науково-технічний журнал "Проблеми керування та інформатики", 2020 This work is devoted to the further development of the study of the arms race models, such as Richardson type models. The simplicity and universality of the basic model are analyzed, successful cases of its application are specified.
А.В. Шатирко +3 more
doaj +1 more source