Results 31 to 40 of about 1,532,255 (309)

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

BORDERLANDS AND ACCOMMODATION: SPANISH SOLDIERS AND AMERINDIAN NATIONS IN LOUISIANA AND FLORIDA (1763-1803)

open access: yesAlmanack, 2021
The treaty of Paris at the end of the Seven Years war meant the addition of Louisiana to the Spanish Empire in 1763 while the treaty of Versailles at the end of the United States war of Independence marked the return of the Floridas under Spanish control,
Soizic Croguennec
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Zombie Army: The Canadian Army and Conscription in the Second World War (Book Review) by Daniel Byers [PDF]

open access: yes, 2018
Review of Zombie Army: The Canadian Army and Conscription in the Second World War by Daniel ...
Bertosa, Brian
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Representasi Sipil-Militer dan Konstruksi Maskulinitas pada Film Jenderal Soedirman (2015)

open access: yesParadigma: Jurnal Kajian Budaya, 2018
Jenderal Soedirman (2015) is a historical film that reveals the story of General Soedirman during the guerrilla war to maintain the Indonesia’s independence.
Hary Ganjar Budiman, Kunto Sofianto
doaj   +1 more source

Battle of Vellinghausen: Lessons Learnt? A Study of the British army in the closing stages of the Seven Years War in Western Europe as studied through the Battle of Vellinghausen [PDF]

open access: yes, 2019
This is a study of the British military actions in Western Germany during the Seven Years War, investigating the army’s ability in combat and analysing its improvements through the case study of the Battle of Vellinghausen.
Dodson, Samuel
core  

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Authority and national security due to the cooperation of the Army of the Islamic Republic of Iran and the Revolutionary Guards Corps with an emphasis on the views of the Supreme Leader Imam Khamenei [PDF]

open access: yesعلوم و فنون نظامی, 2020
The Army of the Islamic Republic of Iran and the Islamic Revolutionary Guards Corps are two military armies of Velayat-e Faqih and the Islamic Republic of Iran's holy system, both of which are defending the country's existence and the political system ...
Mohsen Rostami, M.Abolfazl Mokhtari
doaj   +1 more source

Canadian Soldiers in West African Conflicts, 1885–1905 [PDF]

open access: yes, 2012
This article examines the role played by Canadians at the turn of the century in West Africa. Though not intended to draw sweeping conclusions about the influence of such operations on the Canadian army as a whole—such analysis must follow at a later ...
Godefroy, Andrew B.
core   +1 more source

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