Results 201 to 210 of about 406,090 (346)

Optogenetic manipulation of an ascending arousal system tunes cortical broadband gamma power and reveals functional deficits relevant to schizophrenia

, 2020
James M. McNally, David D. Aguilar, Fumi Katsuki, Leana K. Radzik, Felipe L. Schiffino, David S. Uygun, James T Mckenna, Robert E. Strecker, Karl Deisseroth, Kevin Spencer, Ritchie E. Brown   +10 more
openalex   +2 more sources

Arousal from slices to humans [PDF]

, 2010
Nebojsa Kezunovic, Christen Simon, James Hyde, Kristen Smith, Paige Beck, Angela K. Odle, Edgar García‐Rill   +6 more
openalex   +1 more source

Memantine treatment in individuals with GRIN gain‐of‐function variants is associated with improvements in behavior, development, and seizure frequency

Epilepsia, EarlyView.
Abstract Objective GRIN‐related disorders due to pathogenic variants in GRIN1, GRIN2A, GRIN2B, or GRIN2D genes are associated with altered N‐methyl‐D‐aspartate receptor (NMDAR) function. Functional changes include gain (GoF) and loss of receptor function (LoF). Clinical reports describing the use of the NMDAR blocker memantine in GRIN‐related disorders
Maike Karnstedt, Riley E. Perszyk, Scott J. Myers, Ellington McDaniels, Marta Somorai, Ingo Borggraefe, Danielle C. M. Veenma, An‐Sofie Schoonjans, Pasquale Striano, Tadeu A. Fantaneanu, Steffen Syrbe, Kristen Park, Wenjuan Chen, Hongjie Yuan, Stephen F. Traynelis, Timothy A. Benke, Johannes R. Lemke, Ilona Krey   +17 more
wiley   +1 more source

Dynamic brain mechanisms supporting salient memories under cortisol. [PDF]

Sci Adv
Huang Y, O'Connor D, Harris BB, Sinha R, Constable RT, Goldfarb EV.   +5 more
europepmc   +1 more source

An Examination of Psychophysiological Sexual Arousal in Bisexual Women

, 2016
Monica Haberl
openalex   +1 more source

Baseline characteristics and feasibility of clinical outcome measures in CDKL5 deficiency disorder: The CANDID observational study

Epilepsia, EarlyView.
Abstract Objective CDKL5 deficiency disorder (CDD) is a rare X‐linked developmental and epileptic encephalopathy caused by loss‐of‐function variants in the CDKL5 gene. Preclinical experiments using enzyme replacement or gene therapies show promise and could be transformative therapies.
Xavier Liogier d'Ardhuy, CANDID Partners, Tricia Cimms, Kristina Lindsten, Marco Rizzo, Alison Skrinar, Peter St. Wecker, Ana Mingorance, Orrin Devinsky   +8 more
wiley   +1 more source

A systematic review and multilevel meta-analysis of the relationship between boredom and arousal. [PDF]

Commun Psychol
Stempfer L, Stoll SEM, Fries J, Pekrun R, Goetz T.   +4 more
europepmc   +1 more source

Skeletal muscle proteomics: carbohydrate metabolism oscillates with seasonal and torpor-arousal physiology of hibernation

, 2011
Allyson G. Hindle, Anis Karimpour‐Fard, L. Elaine Epperson, Lawrence Hunter, Sandra L. Martin   +4 more
openalex   +2 more sources

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Functional neuroanatomy of dopaminergic arousal systems: implications for the wake-promoting effect of psychostimulants, with particular reference to modafinil. [PDF]

Front Neuroanat
Szabadi E.
europepmc   +1 more source