Results 61 to 70 of about 137,760 (296)

Emerging Hydrochromic Metal Halide Perovskites

open access: yesAdvanced Optical Materials, EarlyView.
Hydrochromic metal halide perovskites (MHPs) are promising candidates for next‐generation smart optical materials owing to their excellent responsiveness, superior reversibility, and highly tunable emission. This review summarizes the latest progress in hydrochromic MHPs and provides general principles for the rational design of advanced hydrochromic ...
Shuohan Li   +5 more
wiley   +1 more source

Unraveling the Role of MDK‐SDC4 Interaction in Pancreatic Cancer‐Associated New‐Onset Diabetes by Single‐Cell Transcriptomic Analysis

open access: yesAdvanced Science, EarlyView.
Midkine (MDK) is a mediator of the interaction between pancreatic cancer and beta cells. MDK, which originated from pancreatic ductal adenocarcinoma cells, exerted deleterious effects on paraneoplastic beta cells by binding to the SDC4 receptor on the beta cell surface and subsequently downregulating the Ras signaling pathway, thereby impairing insulin
Zengyu Feng   +7 more
wiley   +1 more source

Interaction Effects of Arousal Level of Positive Ambient Emotion and Advertisement Type on Product Evaluation

open access: yesAsia Marketing Journal, 2016
The purpose of this study is to show that the effectiveness of utilitarian versus hedonic attributefocused advertisement on product evaluation depends on the arousal level of positive emotion, and to explore mediation effect of cognitive response to ...
Nak Hwan Choi, Tamir Oyunbileg
doaj   +1 more source

Rational Design of Inner Ear Drug Delivery Systems

open access: yesAdvanced Science, EarlyView.
Hearing loss is a common disease affecting many people, and inner ear lesions are one of the most important causes. This review focuses on the treatment of inner ear hearing loss by drug delivery systems. It includes the current methods and technologies developed, and it predicts possible directions.
Xiayidan Maimaitikelimu   +5 more
wiley   +1 more source

The mediating role of cognitive arousal in the relationship between impulsivity and sleep quality among college students: a random intercept cross-lagged panel analysis

open access: yesScientific Reports
Impulsivity, cognitive arousal, and sleep quality are critical factors affecting college students’ well-being and academic performance. While impulsivity negatively influences sleep quality, the mediating role of cognitive arousal remains underexplored ...
Erum Rehman   +5 more
doaj   +1 more source

Behavioural and neural signatures of perceptual decision-making are modulated by pupil-linked arousal

open access: yeseLife, 2019
The timing and accuracy of perceptual decision-making is exquisitely sensitive to fluctuations in arousal. Although extensive research has highlighted the role of various neural processing stages in forming decisions, our understanding of how arousal ...
Jochem van Kempen   +6 more
doaj   +1 more source

Parasubthalamic Glutamatergic Neurons Coordinate Cardiovascular Homeostasis and Locomotion in Mice

open access: yesAdvanced Science, EarlyView.
PSTNVglut2 neurons function as a new central baroreflex hub via projections to the NTS, modulating parasympathetic cardiac output to maintain cardiovascular homeostasis while synchronously regulating locomotion. Blood pressure fluctuations negatively correlate with locomotor performance.
Ming‐Xuan Lu   +8 more
wiley   +1 more source

Calcitonin Gene‐Related Peptide (CGRP)‐Expressing Neurons in the External Lateral Parabrachial Area Regulate Pain‐Induced Sleep Disturbances

open access: yesAdvanced Science, EarlyView.
Lynch et al., identified novel targets on the wake‐promoting pathways that can effectively treat pain‐induced sleep disturbances. The authors demonstrated that Calcitonin gene‐related peptide‐expressing neurons (CGRP) in the external lateral parabrachial nucleus (PBelCGRP) serve as the primary relay node for pain stimuli that cause sleep disruption ...
Nicole Lynch   +13 more
wiley   +1 more source

A highly tunable dopaminergic oscillator generates ultradian rhythms of behavioral arousal

open access: yeseLife, 2014
Ultradian (∼4 hr) rhythms in locomotor activity that do not depend on the master circadian pacemaker in the suprachiasmatic nucleus have been observed across mammalian species, however, the underlying mechanisms driving these rhythms are unknown. We show
Ian D Blum   +6 more
doaj   +1 more source

Dysfunctional Decidual CD4+T Cells Induce Recurrent Pregnancy Loss via Palmitoylation‐Dependent Tim‐3 Lysosomal Sorting and Degradation

open access: yesAdvanced Science, EarlyView.
Dysfunctional decidual CD4+T cells induce recurrent pregnancy loss via palmitoylation‐dependent Tim‐3 lysosomal sorting and degradation. The integrated bioinformatics, proteomic, functional and model studies elucidate that Tim‐3 is palmitoylated by ZDHHC3 at Cys9. Sortilin bound to and directed palmitoylated Tim‐3 toward lysosome degradation, resulting
Liyuan Cui   +6 more
wiley   +1 more source

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