Results 31 to 40 of about 1,619 (116)
Empowering precision medicine through high performance computing clusters [PDF]
, 2018 The role of High Performance Computing (HPC) in Medicine is greatly increase in these last years, moving from basic research to the clinics. With the advent of Next Generation Sequencing (NGS) technologies, diverse areas of human health have been ...
Castrignanò Tiziana +2 more
core +3 more sources
Case Reports in Nephrology, Volume 2025, Issue 1, 2025.Autosomal recessive polycystic kidney disease (ARPKD) is a form of hereditary cystic disease with a highly variable phenotypic expression that ultimately leads to chronic kidney disease. Severe cases may warrant surgical intervention with unilateral or bilateral nephrectomy to alleviate thoracic and abdominal compression from massive nephromegaly ...
Ana Nevarez Gilbert +3 more
wiley +1 more source
Nephronophthisis: a genetically diverse ciliopathy. [PDF]
, 2011 Nephronophthisis (NPHP) is an autosomal recessive cystic kidney disease and a leading genetic cause of established renal failure (ERF) in children and young adults.
Eley, L. +3 more
core +4 more sources
Physiological Reports, Volume 13, Issue 2, January 2025.Abstract Polycystic kidney diseases (PKD) are genetic disorders which disrupt kidney architecture and function. Autosomal recessive PKD (ARPKD) is a rare form of PKD, caused by mutations in PKHD1, and clinically more severe than the more common autosomal dominant PKD (ADPKD).
Lauren G. Russell +11 more
wiley +1 more source
Antenatal oligohydramnios of renal origin: long-term outcome [PDF]
, 2017 Background. Prognosis of fetuses with renal oligohydramnios (ROH) is often still regarded as poor. Neonatal complications and the long-term follow-up of fetuses with ROH in two pediatric centres are described. Method.
Kemper, Markus J. +3 more
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Caroli's Syndrome with Autosomal Recessive Polycystic Kidney Disease in a Two Month Old Infant [PDF]
, 2006 Caroli's syndrome is a rare congenital disorder that involves intrahepatic bile duct ectasia and congenital hepatic fibrosis, frequently seen with concomitant autosomal recessive polycystic kidney disease (ARPKD). Literature on infants with ARPKD is rare.
Hur, Yoon Jeong +5 more
core +2 more sources
Pediatric Transplantation, Volume 28, Issue 7, November 2024.Reduced mycophenolate mofetil with a sufficient trough tacrolimus level in a population of mainly corticosteroid‐free pediatric kidney transplant recipients did not lead to unacceptable alloimmunity. ABSTRACT Background Kidney transplantation is the best treatment for end‐stage kidney disease but requires immunosuppressive medications, which have ...
Ann‐Maria Gramkow +5 more
wiley +1 more source
Autosomal dominant polycystic kidney disease [PDF]
, 2015 Polycystic kidney disease (PKD) is the commonest life-threatening genetic disease, affecting 12.5 million people worldwide. It is found in all races and occurs equally in men and women.
Attard, Stephanie
core +1 more source
MedComm, Volume 5, Issue 10, October 2024.Four main applications of organoids. The main applications of organoids include the construction of disease models, drug screening and toxicity evaluation, precision medicine, and regenerative medicine. Abstract Organoids are miniature, highly accurate representations of organs that capture the structure and unique functions of specific organs ...
Qigu Yao +6 more
wiley +1 more source
Combined paediatric liver-kidney transplantation: analysis of our experience [PDF]
, 2014 Thesis (M.Med.(General Surgery)--University of the Witwatersrand, Faculty of Health Sciences, 2014.Background. Renal insufficiency is increasingly common in end-stage liver disease and allocation of livers to this category of patient has escalated.
Strobele, Bernd
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