Results 31 to 40 of about 378,418 (314)
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Thiran Filters for Wideband DSP-Based Multi-Beam True Time Delay RF Sensing Applications
SensorsThe ability to sense propagating electromagnetic plane waves based on their directions of arrival (DOAs) is fundamental to a range of radio frequency (RF) sensing, communications, and imaging applications.
Sirani M. Perera +2 more
doaj +1 more source
Comparative Study between Several Direction of Arrival Estimation Methods
Journal of Telecommunications and Information Technology, 2014 In this paper a comparative study, restricted to one-dimensional stationary case, between several Direction of Arrival (DOA) estimation algorithms of narrowband signals is presented.
Youssef Khmou, Said Safi, Miloud Frikel
doaj +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
EURASIP Journal on Advances in Signal Processing, 2005 We introduce a realistic frequency-dependent channel model for ultra-wideband (UWB) communication systems and develop a generalized broadband Capon spatial spectrum estimator for localization of multiple incoherently distributed scattering clusters. The
Chen Yifan, Dubey Vimal K
doaj +1 more source
IEEE Access, 2018 This paper discusses the localization problem for strictly noncircular sources based on Doppler shifts and angle of arrival (AOA). The conventional location methods, called two-step methods, first extract measurement parameters from the signals, and then
Tianzhu Qin +3 more
doaj +1 more source
Optimization of Printing Parameters for Digital Light Processing 3D Printing of Hollow Microneedle Arrays [PDF]
, 2021 Essyrose Mathew +3 more
openalex +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source