Results 41 to 50 of about 7,913 (283)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Perbandingan Pengaruh Penempatan Arrester Sebelum dan Sesudah Fco sebagai Pengaman Transformator 3 Phasa terhadap Gangguan Surja Petir di Penyulang Pandean Lamper 5 Rayon Semarang Timur [PDF]

, 2014
Azis Nurrochma Wardana, Arkhan Subari, in paper comparison of the effect of placement arrester before and after FCO as safety of 3 phase transformator from interruption of lightning at Pandean Lamper 5 Feeder, East Semarang explain that problem of the ...
Subari, A. (Arkhan), Wardana, A. N. (Azis)   +1 more
core  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

An overview of biodiesel energy [PDF]

, 2020
Over the last ten years’ attention to biofuels production has increased dramatically and become crucial. One of the main factors is the rise in world oil prices, coupled with the abatement of greenhouse gas emissions and concerns about energy security ...
Abd Halim, Muhamad Fazli, Khalid, Amir, Leman, Abdul Mutalib, Mohamed Sunar, Norshuhaila   +3 more
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Analisis Persebaran Medan Listrik Pada Lightning Arrester 20kV Menggunakan Finite Element Method

Jurnal Teknik ITS, 2017
Lightning Arrester adalah perangkat semikonduktor yang digunakan dalam sistem tenaga listrik untuk melindungi peralatan terhadap petir dan switching tegangan lebih. Alat pelindung terhadap gangguan petir ini berfungsi melindungi peralatan sistem tenaga
A A Gd Dharma Putera, I Made Yulistya Negara, Daniar Fahmi   +2 more
doaj  

STUDY ON SURGE ARRESTER PERFORMANCE DUE TO LIGHTNING STROKE IN 20 KV DISTRIBUTION LINES [PDF]

, 2009
Abstrak Electric energy has been transmiting from power station to end user with transmission and distribution lines. Lightning strokes are problems that occure in transmission and distribution lines and make them fault when the electric energy were ...
Liliyana NS, Liliyana NS, Syakur, Abdul, Warsito, Agung   +2 more
core  

Investigation of Diagnostic Techniques for Metal Oxide Surge Arresters [PDF]

, 2005
Gapless metal oxide surge arresters(MOSA)have been available in the market for many years since they were first introduced in the 1970's. The aim of this study is to investigate some reliable diagnostic techniques to assess the condition of a metal oxide
Mardira, Karl P., Saha, Tapan K., Sutton, R. A.   +2 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Analysis of Surge Propagation with Lightning Arrester using FDTD for 25 kV-AC Transmission Line [PDF]

, 2017
This paper analyzes lightning surge propagation and reflection as the surge arrives at a lightning arrester. Telegraphist equations have been used to characterize the voltage and current of a travelling wave in a lossless power transmission line and ...
Aodsup, K. (Kokiat), Kulworawanichpong, T. (Thanatchai)   +1 more
core