Results 221 to 230 of about 84,426 (302)

Deciphering pro‐arrhythmogenic mechanisms of EPAC in human atrial cardiomyocytes

The Journal of Physiology, EarlyView.
Abstract figure legend This study aimed to investigate the effect of exchange proteins directly activated by cAMP (EPAC) on the regulation of human atrial cardiomyocyte electrophysiology and their potential involvement in the onset of atrial fibrillation (AF).
Arthur Boileve, Margaux Aize, Maximin Détrait, Laura Brard, Adrien Leboyer, Pierre‐Antoine Dupont, Alexandre Lebrun, Vladimir Saplacan, Christophe Simard, Fabien Brette, Frank Lezoualc'h, Laurent Sallé   +11 more
wiley   +1 more source

Fracture and Perforation of Coronary Sinus Lead due to Retained Guide Wire During Index Cardiac Resynchronization Therapy Implantation. [PDF]

J Arrhythm
Kara SC, Canpolat U, Aytemir K.
europepmc   +1 more source

Combined inhibition of atrial‐specific potassium currents as a possible anti‐arrhythmic drug therapy: A match made in silico

The Journal of Physiology, EarlyView.
Vladimír Sobota
wiley   +1 more source

Non‐invasive assessment of integrated cardiorespiratory network dynamics after physiological stress in humans

The Journal of Physiology, EarlyView.
Abstract figure legend This study aimed to develop a non‐invasive method for visualizing the cardiorespiratory network under baseline conditions and following isolated or combined exposure to hypoxia, exercise, and sleep deprivation. Twenty‐two healthy participants underwent assessments at rest and after normobaric hypoxia (FIO2${{F}_{{\mathrm{I ...
Cecilia Morandotti, Louise Rigny, Thomas B. Williams, Juan I. Badariotti, Matt Miller‐Dicks, Amar S. Bhogal, Shachula Han, Jo Corbett, Michael J. Tipton, Joseph T. Costello, Ali R. Mani   +10 more
wiley   +1 more source

Supraventricular Tachycardias Using Multiple Accessory Pathways. [PDF]

J Arrhythm
Yamada T.
europepmc   +1 more source

Computational modelling of cardiac fibroblast signalling reveals a key role for Ca2+ in driving atrial fibrillation‐associated fibrosis

The Journal of Physiology, EarlyView.
Abstract figure legend A pre‐existing fibroblast signalling model was enhanced by integrating atrial‐specific components and reactions linked to atrial fibrosis and atrial fibrillation (AF). The analysis highlights the central role of Ca2⁺ signalling in driving profibrotic responses to AF‐relevant stimuli, angiotensin‐II and transforming growth factor ...
Najme Khorasani, Haibo Ni, Jeffrey J Saucerman, Dobromir Dobrev, Stefano Morotti, Eleonora Grandi   +5 more
wiley   +1 more source

Evaluation of palpitations in pregnancy using an ambulatory event monitor. [PDF]

Am Heart J Plus
Navya A, Ramy Z, Devansh P, Beshoy I, Nour T, Varun S, Sadeer A, Judy M, Chantal EA.   +8 more
europepmc   +1 more source

Mechanistic insights into sex differences in atrial electrophysiology and arrhythmia vulnerability through sex‐specific computational models

The Journal of Physiology, EarlyView.
Abstract figure legend Sex‐specific models of the human atrial myocyte in normal sinus rhythm (nSR) and chronic atrial fibrillation (cAF) revealed increased alternans susceptibility in cAF males and DADs in females, driven primarily by ICaL and ryanodine receptor remodelling.
Nathaniel T. Herrera, Haibo Ni, Charlotte E. R. Smith, Yixuan Wu, Dobromir Dobrev, Stefano Morotti, Eleonora Grandi   +6 more
wiley   +1 more source

Ebstein's anomaly with life-threatening arrhythmia: an unusual cardiovascular manifestation of Williams syndrome - a case report. [PDF]

BMC Cardiovasc Disord
Schouw ME, Koopmann TT, Blom NA, Stöger JL, Barge-Schaapveld DQCM, Bökenkamp R.   +5 more
europepmc   +1 more source

Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes

The Journal of Physiology, EarlyView.
Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière, Thomas Boulin, Maëlle Jospin, Alexandre Janin, Gilles Millat, Philippe Chevalier, Olga Andrini   +6 more
wiley   +1 more source