Results 51 to 60 of about 188,536 (266)

Impact of Food Desert Residence on Ischemic Stroke and Hospitalization Risk in Atrial Fibrillation Patients

JACC: Advances
Background: Extensive research has been done on the connection between dietary habits and cardiovascular health; however, the impact of food desert residence on atrial fibrillation (AF) patients remains unclear.
Eleanor Christianson, BSPH, Yingshuo Liu, MS, Alexander Dahl, BS, Eli Tsakiris, BS, Joe Abi-Rached, BS, Cecile McGarvey, BS, Nour Chouman, MD, Ghassan Bidaoui, MD, Ala Assaf, MD, Hadi Younes, MD, Mayana Bsoul, MD, Yishi Jia, MS, Yuxuan Gu, MS, Chanho Lim, MS, Omar Kreidieh, MD, Amitabh Pandey, MD, Swati Rao, MD, Xiang Li, PhD, Han Feng, PhD, Nassir Marrouche, MD   +19 more
doaj   +1 more source

Mitochondrial Dysfunction Unravels the Potential Molecular Link Between Night Shift Work‐Related Circadian Disruption and Elevated Blood Pressure in Human and Mouse Models

Advanced Science, EarlyView.
This diagram illustrates that night shift work disrupts circadian clock genes (like CLOCK, BMAL1) in both humans and mice. This disruption leads to mitochondrial dysfunction (imbalanced fusion/fission proteins) and increased oxidative stress, which is identified as the primary mechanism ultimately causing elevated blood pressure.
Zhaoqiang Jiang, Yifan Dou, Yingnan Lei, Shuang Liu, Jialin Zhou, Jiaping Li, Huadong Xu, Lingfang Feng, Yongxin Li, Chuyan Zhang, Tao Li, Jianfei Wang, Xing Zhang, Xinran Wang, Luyao Liu, Jingjing Zhang, Jianlin Lou   +16 more
wiley   +1 more source

Right-heart reverse remodeling and heart failure symptom outcomes after catheter ablation in patients with persistent atrial fibrillation, heart failure, and functional tricuspid regurgitation

Frontiers in Cardiovascular Medicine
BackgroundPersistent atrial fibrillation (AF) and heart failure (HF) may promote right-heart remodeling and functional tricuspid regurgitation (FTR). Evidence regarding right-heart changes after first AF ablation in patients with persistent AF, HF, and ...
Ya Shen, Peng Wang, Yihui Du, Junli Jia, Yanshan Wang   +4 more
doaj   +1 more source

BIN1 and ALDH1B1 Deficiency in Colonic Smooth Muscle Drives Mitochondrial Dysfunction and Fibrosis in Slow‐Transit Constipation

Advanced Science, EarlyView.
Slow‐transit constipation (STC) is a disabling motility disorder with unclear smooth‐muscle mechanisms. Spatial proteomic analysis of STC patient colon reveals both the central pathogenic role of smooth muscle cells (SMCs) in STC and novel regulators of intestinal motility, BIN1 and ALDH1B1.
Jianbo Liu, Hao Zhang, Wenhao Qiao, Ran Liu, Jie Sun, Xiaopei Li, Qin Li, Dongbo Zhao, Dawei Chen, Jingxin Li, Shuxiao Dong   +10 more
wiley   +1 more source

Celastrol‐Loaded Conductive Hydrogel Mitigates Myocardial Ischemia‐Reperfusion Injury and Restores Electrophysiological Function

Advanced Science, EarlyView.
Schematic illustration of the Pluronic F127 diacrylate/gelatin methacryloyl/poly(3,4‐ethylenedioxythiophene):poly(styrenesulfonate)/celastrol hydrogel (FGPC) for localized myocardial ischemia–reperfusion injury treatment. FGPC combines sustained celastrol delivery with PEDOT:PSS‐mediated conductive support to attenuate acute oxidative/inflammatory ...
Shixin Wang, Shaojie Chen, Chengzong Li, Hongyi Cheng, Jincheng Jiao, Xiafeng Peng, Yike Zhang, Wei Sun, Feng Zhang, Chang Cui, Minglong Chen   +10 more
wiley   +1 more source

Health‐related quality of life following total minimally invasive, hybrid minimally invasive or open oesophagectomy: a population‐based cohort study

BJS (British Journal of Surgery), EarlyView., 2020
All patients operated for oesophageal cancer in Sweden from 2013 to April 2018 were identified, and 246 patients were recruited to this population‐based nationwide Swedish study. The results show that longitudinal health‐related quality of life after minimally invasive oesophagectomy was similar to that of the open surgical approach.
F. Klevebro, J. H. Kauppila, S. Markar, A. Johar, P. Lagergren   +4 more
wiley   +1 more source

Biventricular / Left Ventricular Pacing in Hypertrophic Obstructive Cardiomyopathy: An Overview

Indian Pacing and Electrophysiology Journal, 2012
Hypertrophic cardiomyopathy (HCM) is an autosomal dominant inherited genetic disease characterized by compensatory pathological left ventricle (LV) hypertrophy due to sarcomere dysfunction.
Radu Vatasescu, MD, Reinder Evertz, MD, Lluis Mont, MD, PhD, Marta Sitges, MD, PhD, Josep Brugada, MD, PhD, Antonio Berruezo, MD, PhD   +5 more
doaj   +1 more source

Synchronization‐Dissipation in the Cardiorespiratory System

Advanced Science, EarlyView.
By modeling central nervous coupling and viscoelastic interactions in the cardiorespiratory system we show that synchronization produces a 10% gain in cardiac efficiency in humans. It is surmised that respiratory sinus arrhythmia improves cardiac pumping efficiency by reducing dynamic stress and power dissipation in the pulmonary vasculature.
Joshua R. Border, Alain Nogaret, Andrew Lefevre, Vishal Jain   +3 more
wiley   +1 more source

An Intraoperative Fluoroscopic Predictor of Successful Micra Implantation on the Right Ventricular Mid‐Septum

Journal of Arrhythmia
Background The Micra transcatheter pacing system has been adopted globally. However, the procedural parameters for safe Micra implantation on the ventricular wall, particularly in the mid‐septum, remain unknown.
Misun Pak, Ken Kakita, Takashi Yamasaki, Tetsuhisa Hattori   +3 more
doaj   +1 more source

Nearly fatal ventricular arrhythmia following pacemaker implantation in a young female with complete heart block

Journal of Arrhythmia, 2019
This case concerns a 24‐year‐old female who developed malignant ventricular tachyarrhythmia a few weeks after pacemaker implantation for complete heart block.
Hussam Ali, Pierpaolo Lupo, Sara Foresti, Guido De Ambroggi, Riccardo Mantovani, Carmine De Lucia, Ilaria Passarelli, Luigi De Ambroggi, Riccardo Cappato   +8 more
doaj   +1 more source