Results 111 to 120 of about 1,486,387 (308)

Hierarchical Superposition Framework Reveals the Complex Effects of Natural Medicine Formulas

Advanced Intelligent Systems, EarlyView.
A novel hierarchical superposition pharmacological model incorporates the principle of hierarchical structures from physics to simulate the spatiotemporal dynamics of drug combinations, to elucidate the universal law underlying drug combination effects. By modeling cross‐level causal transmission and attenuation, it advances beyond traditional additive
Weifeng Liang, Dingsi Xiang, Shengli Mi, Jiajun Huang   +3 more
wiley   +1 more source

Parametric Design of Continuum Robots Using Interlocking Ball Joints

Advanced Intelligent Systems, EarlyView.
Herein, a parametric design methodology is introduced for producing a wide variety of modular ball joint‐based continuum robots. It is demonstrate by designing a magnetically actuated continuum robot for cardiac ablations. The methodology is released as an open‐source computer‐assisted design extension that automatically designs continuum robots based ...
Alexandre Mesot, Quentin Boehler, Florian Heemeyer, Sean Lyttle, Buse Aktaş, Bradley J. Nelson   +5 more
wiley   +1 more source

Collaborative Multirobot Navigation‐Assisted Magnetic Catheter Guidance and Shape Perception with Vascular Ultrasound and Electromagnetic Tracking

Advanced Intelligent Systems, EarlyView.
The article develops a collaborative multirobot navigation system‐assisted magnetic catheter guidance and shape perception method using the information fusion of robotic vascular ultrasound imaging and electromagnetic tracking to reconstruct the 3D catheter's shape and vasculature. Results verify the effectiveness of the system and the potential of the
Zhengyang Li, Junan Li, Magejiang Yeerbulati, Shurun Liang, Yechen Zhang, Qingsong Xu   +5 more
wiley   +1 more source

A Memristor‐Based Event‐Driven Reservoir Computing System for Cardiac Arrhythmia Detection

Advanced Intelligent Systems, EarlyView.
A low‐power, memristor‐assisted system is developed for real‐time arrhythmia detection in wearable electrocardiograph (ECG) monitoring. It integrates a level‐crossing encoder, a reservoir computing module, and a memristor crossbar to compress, process, and classify signals efficiently.
Hanrui Li, Dayanand Kumar, Nazek El‐Atab   +2 more
wiley   +1 more source

Current Nationwide Landscape of Cardiac Surgery for Children With Trisomy 18 in Japan

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Despite the increasing number of retrospective cohorts describing successful cardiac surgery for children with trisomy 18, no consensus has been reached among healthcare providers regarding cardiac surgery in Japan. This study provided a benchmark to facilitate consensus building by assessing a nationwide surgical database in Japan. A total of
Shintaro Nemoto, Hisateru Tachimori, Tomoki Kosho, Kanta Kishi, Noboru Motomura, Yasutaka Hirata   +5 more
wiley   +1 more source

The HRAS Variant c.175G>A (p.Ala59Thr) Causes a Predominantly Ectodermal Phenotype Lacking Classic Costello Syndrome Features

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Costello syndrome (CS) is a rare dominant HRAS RASopathy characterized by curly hair, cardiac abnormalities, craniofacial anomalies, and developmental delay. HRAS codon 58, 59, and 60 variants are associated with milder phenotypes. We describe a three‐generation family with a previously unreported heterozygous HRAS variant c.175G>A (p.Ala59Thr)
Nikole Rautiainen, Eveliina Brandt, Kaisa Kettunen, Outi Elomaa, Sirpa Kivirikko, Leila Jeskanen, Katriina Lappalainen, Nelli Sjöblom, Juha Kere, Katariina Hannula‐Jouppi, Liisa Harjama   +10 more
wiley   +1 more source

Management of Cardiovascular Health Issues in Turner Syndrome: Expert Insights and Expanded Recommendations From the 2024 Guideline Development Team

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Turner syndrome (TS) is frequently complicated by congenital heart disease (CHD). While left‐sided lesions such as bicuspid aortic valve (BAV) and coarctation of the aorta are the most common structural heart lesions in TS, other anomalies, such as aortic arch malformations, hypoplastic left heart syndrome (HLHS), persistent left superior vena
Katya de Groote, Sheetal R. Patel, Kristian Havmand Mortensen, Isabel Witvrouwen, Anthonie Duijnhouwer, Nicole M. Brown, Jasmine Grewal, Kathryn C. Chatfield, Aaron T. Dorfman, Siddharth K. Prakash   +9 more
wiley   +1 more source

Gender Differences in Rates of Arrhythmias, Cardiac Implantable Electronic Devices, and Diagnostic Modalities Among Sarcoidosis Patients. [PDF]

Cureus, 2020
Durugu S, Gonuguntla K, Patil S, Rojulpote C, Vyata V, Karambelkar P, Narayanareddy P, Vuthaluru K, Bhattaru A.   +8 more
europepmc   +1 more source

COVID-19 and cardiac arrhythmias

Heart Rhythm, 2020
Anjali Bhatla, Michael M. Mayer, S. Adusumalli, Matthew C. Hyman, E. Oh, A. Tierney, Juwann Moss, Anwar A. Chahal, George Anesi, S. Denduluri, C. Domenico, Jeffrey S. Arkles, B. Abella, J. Bullinga, D. Callans, S. Dixit, A. Epstein, D. Frankel, Fermin C. García, Ramanan Kumareswaram, S. Nazarian, Michael P. Riley, P. Santangeli, R. Schaller, G. Supple, D. Lin, F. Marchlinski, R. Deo   +27 more
semanticscholar   +1 more source

Strategies for optimization of hypoglycemia rat models

Animal Models and Experimental Medicine, EarlyView.
This review focuses on rat models for studying the short‐term and long‐term effects of mild and severe hypoglycemia. We explored the physiological mechanisms to understand the consequences of hypoglycemia in rat experimental models. This study sheds light on uncovering the therapeutic potential for hypoglycemic patients and its efficacy in mitigating ...
Lee Yeong Zher, Eason Kong Qi Zheng, Rayneshia Elaura Raymond, Ye Zhen Jie, Christina Gertrude Yap   +4 more
wiley   +1 more source