Results 151 to 160 of about 10,886 (218)

Mapping the Global Clinical Landscape of Pharmacological Therapies for Heart Failure With Preserved Ejection Fraction: An Analysis Based on ClinicalTrials.gov (2003–2025)

open access: yesiMetaMed, EarlyView.
This study analyzed 236 heart failure with preserved ejection fraction (HFpEF) pharmacological trials registered on ClinicalTrials.gov from 2003 to 2025, revealing a post‐2016 surge (76.3%), U.S. dominance (58.5%), and prominence of SGLT2 inhibitors/novel therapies (each 13.1%).
Yucheng Hou   +6 more
wiley   +1 more source

Early gut microbial and metabolic dysregulation with subclinical cardiac alterations in a nonhuman primate model of Rett syndrome

open access: yesiMeta, EarlyView.
Longitudinal multi‐omics profiling of a nonhuman primate Rett syndrome (RTT) model reveals early systemic alterations. RTT monkeys exhibited postnatal growth retardation, intestinal structural abnormalities, and low‐grade systemic inflammation. Gut microbiome analysis showed delayed microbial maturation and age‐discordant dysbiosis, including altered ...
Ting Zhang   +8 more
wiley   +1 more source

Beyond Traditional Screening: The Future of Heart Failure Detection With Biomarkers and AI

open access: yesiNew Medicine, EarlyView.
Advancing HF Screening: Integrating Technology and Risk Factors Across Eras. This diagram provides a comprehensive review of the historical developments and projected trends of heart failure (HF) screening methodologies, with the prevalent risk factors for HF depicted at the base.
Xiaofeng Fang   +9 more
wiley   +1 more source

Genetic Biomarkers in the Risk Assessment of Sudden Cardiac Events: A Personalized Approach

open access: yesiNew Medicine, EarlyView.
Genetic insights into the risk assessment of sudden cardiac events. ABSTRACT Sudden cardiac events are the leading cause of death worldwide. Conventional risk stratification methods, which largely depend on clinical history, imaging, and electrocardiography, are usually inadequate for identifying high‐risk individuals, especially those without visible ...
Shrikant Verma   +5 more
wiley   +1 more source

Compressed Sensing‐Accelerated 3.0 T Noncontrast‐Enhanced CMRA: Diagnostic Efficacy for Coronary Artery Stenosis

open access: yesiRADIOLOGY, EarlyView.
This bar chart illustrates the diagnostic performance of coronary magnetic resonance angiography (CMRA) for detecting ≥ 50.00% coronary artery stenosis at the segment, vessel, and patient levels, including sensitivity, specificity, positive predictive value, negative predictive value, and accuracy.
Zhengfu Wang   +5 more
wiley   +1 more source

The Effects of Angiotensin Receptor Neprilysin Inhibitor on Endoplasmic Reticulum Stress in Doxorubicin‐Mediated Cardiomyopathy‐Associated Heart Failure Model in Rats

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT One of the most serious complications associated with the use of the chemotherapeutic agent doxorubicin (DOX) is cardiomyopathy. Although cardioprotective drugs such as angiotensin receptor‐neprilysin inhibitors (ARNI) are used to prevent cardiomyopathy in DOX patients, no studies have reported the relationship between ARNI and endoplasmic ...
Mert Unvan   +3 more
wiley   +1 more source

Large Hydatid Cyst in the Cardiac Interventricular Septum: A Rare Case Report and Literature Review

open access: yesJournal of Clinical Ultrasound, EarlyView.
Hydatid disease is a parasitic disease with a high incidence in pastoral areas in Tibet. The heart is an uncommon location of echinococcosis, and involvement of the interventricular septum is even rarer. This disease can remain asymptomatic for a long time, but may result in cardiac tamponade and sudden death.
Lin Gao, Yixiu Zhang, Xiao Yang
wiley   +1 more source

Asymptomatic Giant Right Ventricular Myxoma in an Adolescent: A Rare Case Report With Favorable Surgical Outcome

open access: yesJournal of Clinical Ultrasound, EarlyView.
We report a 13‐year‐old female with a giant right ventricular myxoma extending to the pulmonary trunk. The tumor was diagnosed by multimodal imaging and completely resected, with favorable short‐term outcomes. ABSTRACT Right ventricular (RV) myxomas account for < 5% of cardiac myxomas and are often asymptomatic, easily overlooked.
Aizezi Maihemu   +3 more
wiley   +1 more source

Comparative diagnostic accuracy study of point of care ultrasound techniques for detection of left atrial enlargement by hospital medicine physicians from archived echocardiogram images

open access: yesJournal of Hospital Medicine, EarlyView.
Abstract Background Left atrial enlargement (LAE) is predictive of cardiovascular morbidity and mortality. Prior studies of point‐of‐care ultrasound (POCUS) interpretation methods for identifying LAE utilized older echocardiographic reference ranges. Objectives Compare the test characteristics of hospitalist‐performed POCUS techniques for identifying ...
Christopher J. Smith   +7 more
wiley   +1 more source

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