Results 171 to 180 of about 339,172 (313)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Optimization and Quality Assessment of Arrival Time Picking for Downhole Microseismic Events. [PDF]

Sensors (Basel), 2022
Leng J, Yu Z, Mao Z, He C.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

On some queueing systems with server vacations, extended vacations, breakdowns, delayed repairs and stand-bys

, 2012
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This research investigates a batch arrival queueing system with a Bernoulli scheduled vacation and random system breakdowns.
Khalaf, Rehab
core  

Pulse arrival time as a surrogate of blood pressure. [PDF]

Sci Rep, 2021
Finnegan E, Davidson S, Harford M, Jorge J, Watkinson P, Young D, Tarassenko L, Villarroel M.   +7 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

When Does a Spin Flip? Arrival Time Distributions and Information Propagation in Discrete Quantum Systems. [PDF]

Entropy (Basel)
Martellini L.
europepmc   +1 more source

Blood pressure altering method affects correlation with pulse arrival time. [PDF]

Blood Press Monit, 2022
Heimark S, Rindal OMH, Seeberg TM, Stepanov A, Boysen ES, Bøtker-Rasmussen KG, Mobæk NK, Søraas CL, Stenehjem AE, Fadl Elmula FEM, Waldum-Grevbo B.   +10 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Visual Perception and Analysis of an Approaching Train at Railway Level Crossings in New Zealand

, 2010
The prevalence of railway level crossing accidents in New Zealand is a high profile issue that has warranted close scrutiny over the last 10 years. However, the incident rate has not decreased. This research examined the possibility that visual illusions
Clark, Helen Elizabeth
core