Results 1 to 10 of about 1,896,648 (245)

Pan-cancer efficacy of pralsetinib in patients with RET fusion–positive solid tumors from the phase 1/2 ARROW trial

open access: yesNature Medicine, 2022
Oncogenic RET fusions occur in diverse cancers. Pralsetinib is a potent, selective inhibitor of RET receptor tyrosine kinase. ARROW (NCT03037385, ongoing) was designed to evaluate pralsetinib efficacy and safety in patients with advanced RET-altered ...
Vivek Subbiah   +2 more
exaly   +2 more sources

Arrow of Causality and Quantum Gravity [PDF]

open access: yesPhysical Review Letters, 2019
Causality in quantum field theory is defined by the vanishing of field commutators for spacelike separations. However, this does not imply a direction for causal effects.
John Francis Donoghue, Gabriel Menezes
exaly   +2 more sources

Solid-Phase Microextraction Arrow for the Sampling of Volatile Organic Compounds in Milk Samples

open access: yesSeparations, 2020
A novel sample preparation method based on the use of the Arrow solid-phase microextraction device was used to extract and preconcentrate volatile organic compounds (VOCs) from milk samples prior to their determination by gas chromatography–mass ...
Natalia Manousi   +2 more
doaj   +2 more sources

Decision Making in the Arrow of Time [PDF]

open access: yesPhysical Review Letters, 2015
We show that the steady-state entropy production rate of a stochastic process is inversely proportional to the minimal time needed to decide on the direction of the arrow of time. Here we apply Wald's sequential probability ratio test to optimally decide
Édgar Roldán   +2 more
exaly   +2 more sources

Identification of a Gravitational Arrow of Time [PDF]

open access: yesPhysical Review Letters, 2014
It is widely believed that special initial conditions must be imposed on any time-symmetric law if its solutions are to exhibit behavior of any kind that defines an "arrow of time." We show that this is not so.
Tim Koslowski, Flavio Mercati
exaly   +2 more sources

Is Time's Arrow Perspectival? [PDF]

open access: yes, 2015
We observe entropy decrease towards the past. Does this imply that in the past the world was in a non-generic microstate? I point out an alternative. The subsystem to which we belong interacts with the universe via a relatively small number of quantities,
Rovelli, Carlo
core   +5 more sources

Analyzing volatiles in brown rice vinegar by headspace solid-phase microextraction (SPME)–Arrow: Optimizing the extraction conditions and comparisons with conventional SPME

open access: yesInternational Journal of Food Properties, 2019
The ability to readily determine the composition of brown rice vinegar is important for quality assurance purposes. To that end, solid–phase microextraction (SPME)–Arrow method was optimized for the determination of volatile organic compounds (VOCs) from
Tae Gyu Nam   +4 more
doaj   +2 more sources

PAL SPME Arrow—evaluation of a novel solid-phase microextraction device for freely dissolved PAHs in water

open access: yesAnalytical and Bioanalytical Chemistry, 2015
After more than 25 years, solid-phase microextraction (SPME) has gained widespread acceptance as a well-automatable and flexible microextraction technique, while its instrumental basis remained mostly unchanged.
Maik A Jochmann, Torsten C Schmidt
exaly   +2 more sources

The study of manuscript titled (Al-Efada ana AlTabaseer )of Abdulla Bin Maymoon [PDF]

open access: yesمجلة جامعة الأنبار للعلوم الإنسانية, 2020
This study deals with rare manuscript with 361 pages talked about a type of weapon which is Arabic arrows in the manuscript titled (Al-EfadawaAl-Tabasur likul ram aw muhier) written by a man from Moroccan named Abdullah Bin Maymoon died in 700 H The ...
Saadi. I. Al-Darraji
doaj   +1 more source

Flourishing in critical dialogue

open access: yesSSM - Mental Health, 2023
We discuss various critiques of the research literature on flourishing. We fully agree with calls for greater attention to qualitative work, to cultural differences, and to questions of power and justice concerning flourishing. We argue, however, that in
Tyler J. VanderWeele   +7 more
doaj   +1 more source

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