Results 101 to 110 of about 1,835,390 (328)

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

open access: yesFEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt   +4 more
wiley   +1 more source

A method to validate viral copy-number assay involving a hybrid amplicon and duplex droplet digital PCR

open access: yesMolecular Therapy: Methods & Clinical Development
Viral copy-number (VCN) assay is a powerful, effective method to quantify toxicity, cellular kinetics, and durability of virus-modified cell therapy products. The qualification and validation of assay requires reference control.
Raymond Wu   +3 more
doaj  

Black Box White Arrow

open access: yes, 2014
The present paper proposes a new and systematic approach to the so-called black box group methods in computational group theory. Instead of a single black box, we consider categories of black boxes and their morphisms. This makes new classes of black box
Borovik, Alexandre   +1 more
core  

Time's Arrow, February 2, 1999 [PDF]

open access: yes, 1999
This is the concert program of the Time's Arrow performance on Tuesday, February 2, 1999 at 8:00 p.m., at the Tsai Performance Center, 685 Commonwealth Avenue, Boston, Massachusetts.
School of Music, Boston University
core  

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

open access: yesFEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel   +2 more
wiley   +1 more source

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

open access: yesFEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche   +2 more
wiley   +1 more source

Conflict Tasks of Different Types Divergently Affect the Attentional Processing of Gaze and Arrow

open access: yesi-Perception, 2018
The present study explored the attentional processing mechanisms of gaze and arrow cues in two different types of conflict tasks. In Experiment 1, participants performed a flanker task in which gaze and arrow cues were presented as central targets or ...
Lingxia Fan   +5 more
doaj   +1 more source

Time's Arrow, January 21, 1999 [PDF]

open access: yes, 1999
This is the concert program of the Time's Arrow performance on Thursday, January 21, 1999 at 8:00 p.m., at the Tsai Performance Center, 685 Commonwealth Avenue, Boston, Massachusetts.
School of Music, Boston University
core  

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

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