Results 171 to 180 of about 1,835,390 (328)

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

The Removal of Cancer by Caustic Arrows and Carbolic Acid [PDF]

J. R. Wolfe
openalex   +1 more source

Sinew‐Backed Bow and Its Arrows. Photographed and produced in 1961 by the University of California Extension Media Center, with Samuel A. Barrett as consultant [PDF]

, 1966
T. M. Hamilton
openalex   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Thermodynamic optimization in laminar and fully developed flow in double pipe heat exchanger with arrow-shaped extended surfaces: A novel design

Case Studies in Thermal Engineering
An innovative design of extended fins in the form of arrow fins is optimized for high performance heat transfer in a double pipe heat exchanger (DPHX).
Ghazala Ashraf, Sardar Bilal, Muhammad Ishaq, Syed Khalid Saifullah, A.S. Alqahtani, M.Y. Malik   +5 more
doaj  

XXVII. On the plants employed by the antient people of Europe for poisoning their arrows [PDF]

C. Coquebert
openalex   +1 more source

Arrows of Mercy [PDF]

, 1970
WILLIAM B. NEFF
openalex   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Direct oxidative coupling of methane into ethylene in a catalyst-enhanced planar solid oxide fuel cell stack reactor

Physics Open
This study presents an efficient method to convert methane into valuable olefins using a Solid Oxide Fuel Cell (SOFC) membrane reactor. Methane, abundant in natural and shale gas, serves as a sustainable feedstock due to its favorable carbon-hydrogen ...
Yeheng He, Fei Meng, George Xing, Kefeng Liu, Shujie Lou, Haicheng Xiao, Yongchun Tang   +6 more
doaj