Sinew‐Backed Bow and Its Arrows. Photographed and produced in 1961 by the University of California Extension Media Center, with Samuel A. Barrett as consultant [PDF]
, 1966 T. M. Hamilton
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TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
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Molecular Oncology, EarlyView.In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton +17 more
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XXVII. On the plants employed by the antient people of Europe for poisoning their arrows [PDF]
C. Coquebert
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The antiquity of bow-and-arrow technology: evidence from Middle Stone Age layers at Sibudu Cave
Antiquity, 2018 L. Backwell +5 more
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Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
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XXXVIII. On the errors in longitude as determined by chronometers at sea, arising from the action of the iron in the ships upon the chronometers. Communicated by J
George Fisher
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Arrow-Cross Men, National Socialists: 1935-1944. By M. Lackó. Studia Historica, Academiae Scientiarum Hungaricae, 61. Budapest: Akadémiai Kiadó, 1969. 112 pp. $6.00. [PDF]
, 1971 István Deák
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Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
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