Results 31 to 40 of about 1,758,752 (301)
The dual nature of TDC – bridging dendritic and T cells in immunity
FEBS Letters, EarlyView.TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley +1 more source
FEBS Letters, EarlyView.In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali +3 more
wiley +1 more source
The connection between Arrow theorem and Sperner lemma [PDF]
arXiv, 2022 It is well known that Sperner lemma is equivalent to Brouwer fixed-point theorem. Tanaka [12] proved that Brouwer theorem is equivalent to Arrow theorem, hence Arrow theorem is equivalent to Sperner lemma. In this paper we will prove this result directly. Moreover, we describe a number of other statements equivalent to Arrow theorem.
arxiv
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
The length of time's arrow [PDF]
, 2008 An unresolved problem in physics is how the thermodynamic arrow of time arises from an underlying time reversible dynamics. We contribute to this issue by developing a measure of time-symmetry breaking, and by using the work fluctuation relations, we ...
A. S. Eddington +6 more
core +2 more sources
Nature Methods, 2011 At a glance Figures View all figures Figure 1: Arrows in scientific diagrams. (a) Well-understood conventions in molecular biology indicated by arrows. (b) Arrows are defined loosely by their geometric shapes and more definitely in context.
openaire +3 more sources
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Functional variation among LPMOs revealed by the inhibitory effects of cyanide and buffer ions
FEBS Letters, EarlyView.This study addresses the inhibition of lytic polysaccharide monooxygenases (LPMOs) by cyanide and explains how and why the magnitude of observed inhibitory effects depends on the way LPMO reactions are setup and on the type of LPMO. Enzymes known as lytic polysaccharide monooxygenases (LPMOs) are mono‐copper polysaccharide‐degrading peroxygenases that ...
Ole Golten +10 more
wiley +1 more source
Zero-Cost, Arrow-Enabled Data Interface for Apache Spark [PDF]
arXiv, 2021 Distributed data processing ecosystems are widespread and their components are highly specialized, such that efficient interoperability is urgent. Recently, Apache Arrow was chosen by the community to serve as a format mediator, providing efficient in-memory data representation.
arxiv
Arbitrary Arrow Update Logic with Common Knowledge is neither RE nor co-RE [PDF]
EPTCS 251, 2017, pp. 373-381, 2017 Arbitrary Arrow Update Logic with Common Knowledge (AAULC) is a dynamic epistemic logic with (i) an arrow update operator, which represents a particular type of information change and (ii) an arbitrary arrow update operator, which quantifies over arrow updates.
arxiv +1 more source