Results 81 to 90 of about 1,896,797 (391)
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
Influences of an Arrow’s Aerodynamic Pressure Center on Recurve Bow Shooting
Applied SciencesAn arrow’s attack angle continuously changes during its flight, which affects the position of the aerodynamic pressure center. To account for the offset between the aerodynamic pressure center and the center of mass of an arrow in recurve bow shooting ...
Wenfeng Shen +5 more
doaj +1 more source
Frontiers in Public Health, 2016 We detail a five-stage protocol to address physical barriers and experimental limitations that have hindered routine pathogen monitoring of wild rats in urban settings.
Michael H Parsons +2 more
doaj +1 more source
Time's Arrow, December 11, 1996 [PDF]
, 1996 This is the concert program of the Time's Arrow performance on Wednesday, December 11, 1996 at 8:00 p.m., at the Tsai Performance Center, 685 Commonwealth Avenue.
School of Music, Boston University
core
Cycles of linear and semilinear mappings
, 2012 We give a canonical form of matrices of a cycle of linear or semilinear mapping V_1 --- V_2 --- ... --- V_t --- V_1 in which all V_i are complex vector spaces, each line is an arrow ---> or
Bass +16 more
core +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Frontiers in Ecology and Evolution, 2015 Wild rats, Rattus spp, have adapted so well to urbanization that humans may be obligatory to their survival. Consequently, rats foul human food sources, predate threatened fauna and serve as reservoirs for disease, costing the US economy $19 billion in ...
Michael H Parsons +3 more
doaj +1 more source
Time's Arrow, December 11, 1997 [PDF]
, 1997 This is the concert program of the Time's Arrow performance on Thursday, December 11, 1997 at 8:00 p.m., at the Tsai Performance Center, 685 Commonwealth Avenue. Works performed were Brandenburg Concerto No. 4, BWV 1049 by Johann Sebastian Bach, Concerto
School of Music, Boston University
core
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source