Lipid Nanoparticle Co‐Delivery of mRNA and a Small Molecule Drug for Oral Cancer Chemoimmunotherapy
Co‐encapsulation of p53 mRNA and the small molecule ciclopirox within a lipid nanoparticle yields an all‐in‐one chemoimmunotherapy for oral squamous cell carcinoma. The platform engages caspase‐driven apoptosis in cancer cells while repolarizing tumor‐associated macrophages, achieving tumor reduction in both p53‐susceptible and p53‐resistant models and
Marshall S. Padilla +15 more
wiley +1 more source
The impact of dolutegravir on the growth of HIV-exposed uninfected infants: an observational cohort study in rural Tanzania. [PDF]
Glanzmann S +16 more
europepmc +1 more source
Combined 2D and 3D X‐ray scattering imaging is used to analyse nanostructural properties in the inferior and superior cortex of 78 human femoral necks from 44 donors. The methodology allows for increased interpretation of nanostructure in a statistically relevant dataset, revealing nanostructural differences in anatomical locations critical to clinical
Torne Tänzer +8 more
wiley +1 more source
Cross domain consistency of aesthetic preference-driven social behavior. [PDF]
Pham TQ, Chikazoe J.
europepmc +1 more source
Ligand‐Mediated Shape Engineering of SWIR InAs Colloidal Quantum Dots for Photodetector Applications
The table of contents: A robust ligand‐engineering strategy is introduced for SWIR InAs CQDs synthesized from amino‐arsine precursors. Bulky OA ligands induce controlled shape evolution, allowing access to >1700 nm absorption under mild conditions. Halide‐based inkification enables photodetectors with 19.1% EQE at 1300 nm and detectivity exceeding 1010
Taewan Kim +5 more
wiley +1 more source
Change in plasma cryptococcal antigen titers in Uganda among outpatients with advanced HIV disease from 2017 to 2022 with rollout of national cryptococcal screening. [PDF]
Poeschla A +6 more
europepmc +1 more source
Optoelectronic Nanofluidic Neural Networks for Ionic Computing
An ion‐based optoelectronic nanofluidic memristor enables neuromorphic computing in aqueous environments. With tunable ionic memory and multimodal synaptic plasticity, it realizes densely connected ionic neural networks capable of image classification, motion prediction, logic computation, and real‐time in‐sensor computing, advancing fully connected ...
Yaxin Huang +10 more
wiley +1 more source
A‐site high‐entropy engineering creates a robust Pr0.2Ba0.2La0.2Sr0.2Ca0.2FeO3‐δ (PBLSCF) perovskite‐based solid oxide fuel cell (SOFC) anode with in situ Fe nanoparticle exsolution to boost fuel oxidation and durability, achieving strong sulfur tolerance and coking resistance.
Lei Wu +10 more
wiley +1 more source
Virologic outcomes on Dolutegravir-based therapy among children and adolescents living with HIV in Thailand: findings from a national registry database. [PDF]
Teeraananchai S +4 more
europepmc +1 more source
Recent Advances in Ferrite‐Based Materials for Biomedical Applications: A Comprehensive Review
Ferrite nanoplatforms are presented as tunable biomedical materials in which synthesis control, cation engineering, defect/morphology regulation, and surface functionalization govern structure–property–bioactivity relationships. These design strategies enable multifunctional applications including MRI contrast, magnetic hyperthermia, targeted drug ...
Pramod D. Mhase +6 more
wiley +1 more source

