Results 91 to 100 of about 484,362 (301)

Getting it Right: Lessons Learned in Applying a Critical Artefact Approach [PDF]

open access: yes, 2009
“Critical artefacts”, the products of critical design (Dunne 1999), prompt reflection rather than satisfy obvious user needs. The author is developing an instrumental use of critical artefacts as part of a human-centred design process.
Bowen, Simon
core  

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang   +10 more
wiley   +1 more source

Digital environments as third spaces: analyses of simple artefacts in the rooms of the MOdE

open access: yesResearch on Education and Media, 2020
With the spread of digital environments that allow the user to design and produce contents, we have asked ourselves whether digital museums can be considered as ‘third spaces’ in which it is possible to exhibit, research, aggregate and re-elaborate, in a
Panciroli Chiara, Russo Veronica
doaj   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende   +26 more
wiley   +1 more source

Löftesrika ringar

open access: yesKulturella Perspektiv, 2005
Wedding rings have strong networks of actors that want them to circulate in wedding rituals, on market places and in human minds. Rings are seen as a "natural" part of wedding ceremonies but are not needed when you get married.
Eva Knuts
doaj   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano   +11 more
wiley   +1 more source

Exploring sociotechnical gaps in an intercultural, multidisciplinary design project [PDF]

open access: yes, 2010
This paper highlights the need for the creation of artefacts that make\ud visible the gap between social requirements and the technical affordances of\ud technology. Augmenting the visibility of this gap can lead to a better integration\ud of the process
Camara, Souleyman   +1 more
core   +1 more source

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann   +17 more
wiley   +1 more source

Kemungkinan Penggunaan Bambu Sebagai Wadah Pada Masyarakat Ulu Leang I

open access: yesBerkala Arkeologi, 1991
Melihat banyaknya jenis bambu yang tumbuh di Indonesia, sangatlah mungkin bahwa berbagai jenis bambu telah dimanfaatkan oleh masyarakat Indonesia sejak masa prasejarah.
Muhammad Hidayat
doaj   +1 more source

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu   +10 more
wiley   +1 more source

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