Results 31 to 40 of about 84,519 (240)

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Agency as assemblage: Using childhood artefacts and memories to examine children’s relations with schooling

open access: yesJournal of Childhood, Education & Society, 2022
In this article, we explore how childhood artefacts and memories might help us think retrospectively about children’s agency and its relationship to schooling and teaching.
Julie C. Garlen   +3 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Interpreting Aboriginal and Torres Strait Islander Art and Artefacts [PDF]

open access: yesMethexis
The artefacts of Aboriginal and Torres Strait Islanders, common with other ethnic peoples, have to be understood not simply as objects that can be described in terms of their physical characteristics and the use made of them, but also as objects that ...
Jānis (John)
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Partage, fête et alliance dans les sociétés arabo-musulmanes

open access: yesRevue d'ethnoécologie, 2020
We develop some aspects of the sharing food, said sharing the salt ; then we evoke the revival of an old institution, among the maghrebian societies : the collective purchase and the sharing of the meat, among those societies, a part of them migrated to ...
Françoise Aubaile-Sallenave
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Comparison of convolutional neural network architectures for robustness against common artefacts in dermatoscopic images

open access: yesDermatology Practical & Conceptual, 2022
Introduction: Automated classification of dermatoscopic images via neural networks shows comparable performance to clinicians in experimental conditions, but can be affected by artefacts like skin markings or rulers.
Florian Katsch   +2 more
doaj   +1 more source

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