Results 61 to 70 of about 484,362 (301)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
History-based visual mining of semi-structured audio and text [PDF]
, 2006 Accessing specific or salient parts of multimedia recordings remains a challenge as there is no obvious way of structuring and representing a mix of space-based and time-based media.
Bouamrane, Matt-Mouley +2 more
core +2 more sources
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Region-enhanced passive radar imaging [PDF]
, 2005 The authors adapt and apply a recently-developed region-enhanced synthetic aperture radar (SAR) image reconstruction technique to the problem of passive radar imaging.
Cetin, Mujdat +2 more
core +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Experimental artefacts in undrained triaxial testing [PDF]
, 2010 For evaluation of the undrained thermo-poro-elastic properties of saturated porous materials in conventional triaxial cells, it is important to take into account the effect of the dead volume of the drainage system.
Ghabezloo, Siavash, Sulem, Jean
core +3 more sources
The quark propagator in momentum space [PDF]
, 1999 The quark propagator is calculated in the Landau gauge at beta=6.0. A method for removing the dominant, tree-level lattice artefacts is presented, enabling a calculation of the momentum-dependent dynamical quark mass.Comment: LATTICE 99(spectrum), 3 ...
Anthony G. Williams +4 more
core +4 more sources
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Observations on daily Life in the communal town of Leopoli-Cencelle [PDF]
, 2017 The civitas of Leopoli-Cencelle, founded by Pope Leo IV (9th cent.), is located in the Tolfa Mountains on the northern edge of the Province of Rome.
Annoscia, GIORGIA MARIA
core +4 more sources
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source