Results 1 to 10 of about 95,251 (337)
ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2 [PDF]
EMBO Journal, 2009 Homologous recombination (HR) and non‐homologous end joining (NHEJ) represent distinct pathways for repairing DNA double‐strand breaks (DSBs). Previous work implicated Artemis and ATM in an NHEJ‐dependent process, which repairs a defined subset of ...
Atsushi Shibata +2 more
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Space Diplomacy and the Artemis Accords [PDF]
The Hague Journal of Diplomacy, 2023 The growth of human activity in outer space is attracting more International Relations (IR) scholar’s attention, enabling an understanding of the involvement of specific groups of actors and the dynamics of political negotiations that lead to concluding
Nancy Riordan +2 more
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Artemis inhibition as a therapeutic strategy for acute lymphoblastic leukemia
Frontiers in Cell and Developmental Biology, 2023 As effective therapies for relapse and refractory B-cell acute lymphoblastic leukemia (B-ALL) remain problematic, novel therapeutic strategies are needed.
Heather A. Ogana +9 more
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Space radiation measurements during the Artemis I lunar mission [PDF]
NatureSpace radiation is a notable hazard for long-duration human spaceflight1. Associated risks include cancer, cataracts, degenerative diseases2 and tissue reactions from large, acute exposures3.
Stuart George +49 more
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Structural analysis of the basal state of the Artemis:DNA-PKcs complex
Nucleic Acids Research, 2022 Artemis nuclease and DNA-dependent protein kinase catalytic subunit (DNA-PKcs) are key components in nonhomologous DNA end joining (NHEJ), the major repair mechanism for double-strand DNA breaks.
Go Watanabe +2 more
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Physical ARTEMIS:DNA-PKcs interaction is necessary for V(D)J recombination
Nucleic Acids Research, 2022 The nuclease ARTEMIS and the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) are involved in the repair of physiological and pathogenic DNA double strand breaks.
Doris
exaly +2 more sources
Structural and mechanistic insights into the Artemis endonuclease and strategies for its inhibition
Nucleic Acids Research, 2021 Artemis (DCLRE1C) is an endonuclease that plays a key role in development of B- and T-lymphocytes and in DNA double-strand break repair by non-homologous end-joining (NHEJ). Artemis is phosphorylated by DNA-PKcs and acts to open DNA hairpin intermediates
Yuliana Yosaatmadja +2 more
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Current OncologyThe aim of this study was to identify Artemis as a predictive biomarker for guiding preoperative chemoradiotherapy in locally advanced rectal cancer. The resection specimens were collected from 50 patients with rectal cancer who underwent preoperative ...
Hai Liu +6 more
doaj +2 more sources
ATHENA,ARTEMIS,HEPHAESTUS: data analysis for X-ray absorption spectroscopy usingIFEFFIT
Journal of Synchrotron Radiation, 2005 Bruce Ravel
exaly +2 more sources
Artemis and its role in cancer [PDF]
Translational OncologyArtemis is a key nuclease involved in the non-homologous end joining repair pathway upon DNA double-stranded breaks and during V(D)J recombination.
Armen Parsyan +4 more
doaj +2 more sources