Results 1 to 10 of about 80,820 (271)

ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2 [PDF]

EMBO Journal, 2009
Homologous recombination (HR) and non‐homologous end joining (NHEJ) represent distinct pathways for repairing DNA double‐strand breaks (DSBs). Previous work implicated Artemis and ATM in an NHEJ‐dependent process, which repairs a defined subset of ...
Atsushi Shibata, Aaron A Goodarzi, Markus Löbrich   +2 more
exaly   +4 more sources

Increased Artemis levels confer radioresistance to both high and low LET radiation exposures [PDF]

Radiation Oncology, 2012
Background Artemis has a defined role in V(D)J recombination and has been implicated in the repair of radiation induced double-strand breaks. However the exact function(s) of Artemis in DNA repair and its preferred substrate(s) in vivo remain undefined ...
Sridharan Deepa M, Whalen Mary K, Almendrala Donna, Cucinotta Francis A, Kawahara Misako, Yannone Steven M, Pluth Janice M   +6 more
doaj   +2 more sources

Artemis and its role in cancer [PDF]

Translational Oncology
Artemis is a key nuclease involved in the non-homologous end joining repair pathway upon DNA double-stranded breaks and during V(D)J recombination.
Armen Parsyan, Vasudeva Bhat, Harjot Athwal, Emily A. Goebel, Alison L Allan   +4 more
doaj   +2 more sources

Correction: Programmed cell death and redox metabolism protect Chlamydomonas reinhardtii populations from the galactic cosmic environment on the Artemis-1 mission. [PDF]

Sci Rep
Hammond TG, Panikkanvalappil SR, Allen PL, Gaikani HK, Nislow C, Giaever G, Zhang Y, Levine HG, Gaza R, Dimapilis D, Wells HW, Russick JM, Durand PM, Birdsall HH.   +13 more
europepmc   +3 more sources

ARTEMIS: An independently validated prognostic prediction model of breast cancer incorporating epigenetic biomarkers with main effects and gene-gene interactions [PDF]

Journal of Advanced Research
Introduction: Breast cancer, a heterogeneous disease, is influenced by multiple genetic and epigenetic factors. The majority of prognostic models for breast cancer focus merely on the main effects of predictors, disregarding the crucial impacts of gene ...
Maojie Xue, Ziang Xu, Xiang Wang, Jiajin Chen, Xinxin Kong, Shenxuan Zhou, Jiamin Wu, Yuhao Zhang, Yi Li, David C. Christiani, Feng Chen, Yang Zhao, Ruyang Zhang   +12 more
doaj   +2 more sources

Spinal Cord Stimulation for Chronic Refractory Neuropathic Pain: A Technical Note Initial Experience of Two cases

Indian Journal of Neurosurgery, 2021
Spinal cord stimulation is an established procedure for relieving chronic neuropathic pain conditions. Although it has been over five decades since the first spinal cord stimulation (SCS) was developed, it has only been used in a few cases in India.
Sanjeev Srivastava, Pawan Goyal, Anurag Sharma, Sanjay K. Rajan, Aditya Gupta   +4 more
doaj   +1 more source

Trends in carbapenem resistance in Pre-COVID and COVID times in a tertiary care hospital in North India

Annals of Clinical Microbiology and Antimicrobials, 2023
Background Carbapenem resistance is endemic in the Indian sub-continent. In this study, carbapenem resistance rates and the prevalence of different carbapenemases were determined in Escherichia coli, Klebsiella pneumoniae, Acinetobacter baumannii ...
Nirupama Chatterjee, Pushpa K. Nirwan, Shruti Srivastava, Ruchi Rati, Lalit Sharma, Priyanka Sharma, Priyambada Dwivedi, Namita Jaggi   +7 more
doaj   +1 more source

Endoscopic ultrasound-guided coiling and glue is safe and superior to endoscopic glue injection in gastric varices with severe liver disease: a retrospective case control study [PDF]

Clinical Endoscopy, 2023
Background/Aims Gastric varices (GV) are present in 25% of cirrhotic patients with high rates of rebleeding and mortality. Data on endoscopic ultrasound (EUS)-guided treatment in severe liver disease (model for end stage liver disease sodium [MELD-Na ...
Kapil D. Jamwal, Rajesh K. Padhan, Atul Sharma, Manoj K. Sharma   +3 more
doaj   +1 more source

Co-Expression Pattern of Artemis Serine 516 Phosphorylation with Indicators Involving in Differentiation, Proliferation and Apoptosis of Human Anagen Hair Follicles: An Immunofluorescence Double-Staining Study

Frontiers in Bioscience-Landmark, 2023
Background: Artemis belongs to the SNM1 gene family, and plays a role in repairing ionizing-radiation-induced DNA double-strand breaks and variable (diversity) joining recombination.
Ru Dai, Zheren Shao, Min Zheng, Xianjie Wu   +3 more
doaj   +1 more source

Artemis inhibition as a therapeutic strategy for acute lymphoblastic leukemia

Frontiers in Cell and Developmental Biology, 2023
As effective therapies for relapse and refractory B-cell acute lymphoblastic leukemia (B-ALL) remain problematic, novel therapeutic strategies are needed.
Heather A. Ogana, Samantha Hurwitz, Chih-Lin Hsieh, Huimin Geng, Markus Müschen, Deepa Bhojwani, Mark A. Wolf, James Larocque, Michael R. Lieber, Yong Mi Kim   +9 more
doaj   +1 more source