Results 231 to 240 of about 15,257 (261)

Prevalence of Molecular Markers of Resistance to Antimalarial Drugs Three Years After Perennial Malaria Chemoprevention in Sierra Leone. [PDF]

Gates Open Res
Chen H, Owusu-Kyei K, Fombah AE, Williams J, García-Fernández C, Rovira-Vallbona E, Bofill A, Quintó L, Figueroa-Romero A, Mac-Abdul F, Samai M, Mayor A, Menéndez C.   +12 more
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FOXO4-AR crosstalk in PCOS: A pivotal mechanism of anovulation. [PDF]

Mol Ther Nucleic Acids
Qian S, Pan G, Fan M.
europepmc   +1 more source

A fast-acting inhibitor of blood-stage P. falciparum with mechanism distinct from artemisinin and chloroquine

Kabeche S, Meister T, Yeh E.
europepmc   +1 more source

Between financial capitalism and humanitarian concerns: value, price and profits of hepatitis C antivirals and artemisinin-based combinations therapies for malaria

, 2016
Maurice Cassier
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The birth of artemisinin

Pharmacology & Therapeutics, 2020
As the first-line antimalarial drugs, artemisinins gained wide acceptance after the emergence of resistance to chloroquine in the 1950s. Artemisinin-based drugs have saved lives, especially in developing countries. The discovery of artemisinin was unique, timely, and fascinating, and the benefits of artemisinin were with far-reaching implications ...
Nan, Ma, Ziyue, Zhang, Fulong, Liao, Tingliang, Jiang, Youyou, Tu   +4 more
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Artemisinin

Reactions Weekly, 2016
Der Pflanzeninhaltsstoff Artemisinin des Einjahrigen Beifus (Artemisia annua) ist durch die Verleihung des Medizinnobelpreises an die chinesische Forscherin Tu Youyou in den Fokus der Offentlichkeit geruckt. Die medizinische Verwendung der Pflanze weist eine lange Tradition auf.
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Chemistry of artemisinin: an overview

Transactions of the Royal Society of Tropical Medicine and Hygiene, 1994
The endoperoxide sesquiterpene lactone, artemisinin, and its derivatives have become increasingly important as antimalarial drugs with impressive activity against multidrug resistant forms of Plasmodium falciparum. Artemisinin has a novel structure among known antimalarial compounds with a unique 1,2,4-trioxane ring that is essential for activity. This
H K, Webster, E K, Lehnert
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Unpacking ‘Artemisinin Resistance’

Trends in Pharmacological Sciences, 2017
Artemisinin and its derivatives, in combination with partner drugs, are currently the most effective treatments for malaria parasite infection. Even though artemisinin has been widely used for decades, its mechanism of action had remained controversial until recently.
Jigang, Wang, Chengchao, Xu, Zhao-Rong, Lun, Steven R, Meshnick   +3 more
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Artemisinins: activities and actions

Microbes and Infection, 2004
Multidrug-resistant malaria caused by Plasmodium falciparum has severely limited treatment options over recent years. Artemisinins are still effective for treating uncomplicated as well as severe malaria, because resistance is not yet clinically apparent. This article reviews some clinically useful properties of artemisinins and how they might work.
Haynes, RK, Krishna, S.
openaire   +3 more sources