Results 31 to 40 of about 673,563 (309)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Exploring the relationship of peripheral total bilirubin, red blood cell, and hemoglobin with blood pressure during childhood and adolescence

Jornal de Pediatria (Versão em Português), 2018
Objective: Total bilirubin is beneficial for protecting cardiovascular diseases in adults. The authors aimed to investigate the association of total bilirubin, red blood cell, and hemoglobin levels with the prevalence of high blood pressure in children ...
Xiao‐tian Chen, Song Yang, Ya‐ming Yang, Hai‐long Zhao, Yan‐chun Chen, Xiang‐hai Zhao, Jin‐bo Wen, Yuan‐rui Tian, Wei‐li Yan, Chong Shen   +9 more
doaj   +3 more sources

Interpretation of arterial blood gases

Türk Kardiyoloji Derneği Arşivi, 2014
Arterial blood gas analysis is a frequently used and extremely useful clinical tool. Doctors of all levels understand the results to varying degrees.
Gülbin Aygencel
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Epidural Spinal Cord Stimulation of Lumbosacral Networks Modulates Arterial Blood Pressure in Individuals With Spinal Cord Injury-Induced Cardiovascular Deficits

Frontiers in Physiology, 2018
Disruption of motor and autonomic pathways induced by spinal cord injury (SCI) often leads to persistent low arterial blood pressure and orthostatic intolerance.
Sevda C. Aslan, Sevda C. Aslan, Bonnie E. Legg Ditterline, Bonnie E. Legg Ditterline, Michael C. Park, Michael C. Park, Claudia A. Angeli, Claudia A. Angeli, Claudia A. Angeli, Enrico Rejc, Enrico Rejc, Yangsheng Chen, Yangsheng Chen, Alexander V. Ovechkin, Alexander V. Ovechkin, Andrei Krassioukov, Andrei Krassioukov, Andrei Krassioukov, Susan J. Harkema, Susan J. Harkema, Susan J. Harkema   +20 more
doaj   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Ratio of the blood flow in liver and splenic arteries in patients with various forms of portal hypertension

Patologìâ, 2015
Each type of portal hypertension has clinical and diagnostic peculiarities, which determines the choice of therapeutic approach and subsequently an outcome. Aim.
A. S. Tugushev, N. V. Tumanskaya, Ye. S. Barskaya, Ye. G. Nordio, I. P. Djos   +4 more
doaj   +1 more source

Study of Oxygen Saturation by Pulse Oximetry and Arterial Blood Gas in ICU Patients: A Descriptive Cross-sectional Study

Journal of Nepal Medical Association, 2020
Introduction: Pulse oximetery is expected to be an indirect estimation of arterial oxygen saturation. However, there often are gaps between SpO2 and SaO2.
Nabin Rauniyar, Shyam Pujari, Pradeep Shrestha   +2 more
doaj   +1 more source

Arterial blood analysis of healthy residents in Huamachuco, Peru (3,164 m): a cross-sectional study [version 2; peer review: 2 approved, 1 not approved]

F1000Research, 2023
Background: Given that arterial blood gas is affected by altitude and ethnicity, establishing reliable reference standards for these values requires analysis of arterial blood at different elevations and locations.
Lissett J. Fernández-Rodríguez, Cecilia Romero-Goicochea, Victor H. Bardales-Zuta   +2 more
doaj   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source