Results 181 to 190 of about 5,145,698 (249)

Bilateral invasive arterial blood pressure monitoring: a novel adjunct for real-time detection of progression in debakey type II aortic dissection. [PDF]

Crit Care
Zhu H, Feng Q, Yan J, Wang J.
europepmc   +1 more source

NCLX Inhibition plus Ca2+ Delivery Potentiates Electroporation and Antitumor Immunity in Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
Electroporation combined with NCLX inhibition and Ca2+ delivery induces mitochondrial Ca2+ overload in PDAC cells, triggering pyroptosis, DAMP release, and antitumor immune activation. Simultaneously, suppression of tumor‐derived SPP1 weakens SPP1–CD44 signaling and remodels macrophages toward an antitumor phenotype, thereby enhancing CD8+ T‐cell ...
Chuanbing Zhao, Long He, Yu Lu, Zanglong Deng, Hongzhen Wei, Yunpeng Zhang, Ming Yang, Tao Yin   +7 more
wiley   +1 more source

Artifact management methodologies for arterial blood pressure signals: A systematic scoping review of human and animal literature. [PDF]

Physiol Rep
Bergmann T, Vakitbilir N, Nemoga-Stout X, Sainbhi AS, Stein KY, Silvaggio N, Hasan R, Moon J, Hayat M, Froese L, Zeiler FA.   +10 more
europepmc   +1 more source

Thioredoxin‐2 Alleviates Osteoporosis by Restraining FOXO3a Nuclear Translocation

Advanced Science, EarlyView.
Endothelial TRX2 preserves bone homeostasis by retaining FOXO3a at mitochondria and limiting TRAIL production. Loss of TRX2 or oxidative stress releases FOXO3a for nuclear translocation, increasing endothelial TRAIL secretion and driving osteoclast formation and bone loss.
Chi Zhan, Zhaocai Zhou, Yue Ding, Rong Lian, Xinyu Li, Xintong Zhang, Jie Cao, Zhonghui Tang, Zhengmei Lin, Zhi Song, Feng He   +10 more
wiley   +1 more source

Comparison of changes in arterial blood pressure and cardiac output during cardiogenic shock development in a porcine model. [PDF]

Intensive Care Med Exp
Svanekjaer L, Larsen JKP, Frederiksen PH, Linde L, Gregers E, Udesen NLJ, Helgestad OK, Banke A, Jensen LO, Lassen JF, Povlsen AL, Schmidt H, Møller JE, Ravn HB.   +13 more
europepmc   +1 more source

RUNX1‐Mediated Hypoxic Signaling Impairs Myogenesis and Promotes Fibrosis in Myopathies

Advanced Science, EarlyView.
Myofiber overgrowth was associated with reduced blood flow and a potential hypoxic state in broiler breast muscle, accompanied by increased RUNX1 expression. Elevated RUNX1 impaired myogenic regeneration, promoted fibrosis, and disrupted the signaling niche required for efficient muscle repair, contributing to pathological degeneration in Wooden Breast
Liang Zhao, Taijiang Hou, Lin Zhang, Feng Gao, Tong Xing   +4 more
wiley   +1 more source

Implementing prehospital invasive arterial blood pressure monitoring in critically ill patients-a prospective observational first year analysis. [PDF]

Scand J Trauma Resusc Emerg Med
Ule J, Hüppe T, Thiel J, Berwanger U, Schlechtriemen T, Conrad D, Merscher B.   +6 more
europepmc   +1 more source

Chinese Expert Consensus on the Clinical Application of Finerenone in Geriatric Comorbidities

AGING MEDICINE, EarlyView.
Mineralocorticoid receptor (MR) overactivation drives inflammation, oxidative stress, and fibrosis in the heart, kidneys, and vasculature, leading to cardiorenal dysfunction. MR signaling promotes hypertrophy, remodeling, and injury through pathways like oxidative stress and inflammation, resulting in vascular stiffness and progressive organ damage ...
Xiaoming Wang, Cuntai Zhang
wiley   +1 more source

The influence of daily air temperature variability on arterial blood pressure: findings from a cross-sectional study in Kaunas city. [PDF]

Sci Rep
Vencloviene J, Radisauskas R, Vaiciulis V, Luksiene D, Tamosiunas A, Bobak M, Kranciukaite-Butylkiniene D.   +6 more
europepmc   +1 more source

Cerebral Hemodynamic Changes in Older Adults With Cognitive Complaints According to the Presence of Peripheral Artery Disease

AGING MEDICINE, EarlyView.
Among 132 older adults, 13 had peripheral artery disease (PAD), identified using the ankle–brachial index. Over approximately 13 months, PAD was associated with increasing middle cerebral artery mean flow velocity, with a significant difference in left‐sided velocity change between groups.
SangMi Noh, Hae‐Eun Shin, YongSoo Shim
wiley   +1 more source