Results 41 to 50 of about 5,145,698 (249)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Adaptive feedback analysis and control of programmable stimuli for assessment of cerebrovascular function [PDF]

, 2013
The assessment of cerebrovascular regulatory mechanisms often requires flexibly controlled and precisely timed changes in arterial blood pressure (ABP) and/or inspired CO2.
Simpson, David M, Potter, John, Bush, Glen, Allen, Robert, Panerai, Ronney B, Birch, Anthony A, Fan, Lingke, Katsogridakis, Emmanuel   +7 more
core   +1 more source

Changes in peripheral arterial blood pressure after resuscitative endovascular balloon occlusion of the aorta (REBOA) in non-traumatic cardiac arrest patients

BMC Emergency Medicine, 2021
Background Resuscitative endovascular balloon occlusion of the aorta (REBOA) may be an adjunct treatment to cardiopulmonary resuscitation (CPR). Aortic occlusion may increase aortic pressure and increase the coronary perfusion pressure and the cerebral ...
Jostein Rødseth Brede, Eivinn Skjærseth, Pål Klepstad, Trond Nordseth, Andreas Jørstad Krüger   +4 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Difference in blood pressure response to ACE-Inhibitor monotherapy between black and white adults with arterial hypertension: a meta-analysis of 13 clinical trials. [PDF]

, 2013
BACKGROUND: Among African-Americans adults, arterial hypertension is both more prevalent and associated with more complications than among white adults. Hypertension is also epidemic among black adults in sub-Saharan Africa. The treatment of hypertension
Luke R Smart, Heiner Grosskurth, Peck, Robert N, Bernhard MW Schmidt, Schmidt, Bernhard MW, Liwa, Anthony C, Fitzgerald, Daniel W, Beier, Rita, Smart, Luke R, Daniel W Fitzgerald, Robert N Peck, Grosskurth, Heiner, Rita Beier, Anthony C Liwa   +13 more
core   +2 more sources

Modelling of the pulsatile blood flow in an arterial tree of retinal vasculature [PDF]

, 2009
This paper was presented at the 2nd Micro and Nano Flows Conference (MNF2009), which was held at Brunel University, West London, UK. The conference was organised by Brunel University and supported by the Institution of Mechanical Engineers, IPEM, the ...
Ganesan, PB, 2nd Micro and Nano Flows Conference (MNF2009), He, S, Xu, H   +3 more
core   +5 more sources

Contribution of the Arterial System and the Heart to Blood Pressure during Normal Aging - A Simulation Study. [PDF]

PLoS ONE, 2016
During aging, systolic blood pressure continuously increases over time, whereas diastolic pressure first increases and then slightly decreases after middle age.
Elira Maksuti, Nico Westerhof, Berend E Westerhof, Michael Broomé, Nikos Stergiopulos   +4 more
doaj   +1 more source

The Distance Monitoring of Blood Pressure as a Tool for Improving of the Quality of Follow-Up Observation of Patients with Arterial Hypertension

Архивъ внутренней медицины, 2021
This article focuses on the distant blood pressure monitoring for patients with arterial hypertension. As numerous studies show, even slightly elevated blood pressure significantly raises the risk of cardiovascular complications.
I. A. Starodubtseva, Yu. A. Sharapova
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source