This study investigates the critical mechanisms underlying pulmonary hypertension progression, with a focus on the novel role of neutrophil‐derived S100A9 in endothelial dysfunction‐mediated pulmonary vascular remodeling. By integrating human lung samples, multi‐omics analyses, animal models, and mechanistic in vitro studies, it is revealed that how ...
Yu Guo+13 more
wiley +1 more source
Biomaterial-based vascularization strategies for enhanced treatment of peripheral arterial disease. [PDF]
Wang H+5 more
europepmc +1 more source
Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset
This study shows that patients at risk of sepsis have a distinct metabolite and lipid signature, including serine and aminoadipic acid, in their serum before clinical diagnosis. A mouse model of sepsis with a compatible serum signature reveals underlying metabolic changes, including mitochondrial adaptation, altered serine‐dependent purine metabolism ...
Lin‐Lin Xu+9 more
wiley +1 more source
Effect of Nordic walking on walking ability in patients with peripheral arterial disease: a meta-analysis. [PDF]
Sun Z, Zhang J, Fang Y, Qian Y.
europepmc +1 more source
Multiscale Organization of Neural Networks in a 3D Bioprinted Matrix
A 3D bioprint model of primary neurons has been engineered with a millimeter‐scale functional neural network, and it recapitulates in vivo transcriptomic features under both normal and disease conditions to the greatest extent. The successful integration of mature neurons and 3D bioprinting signifies a major advance in neuroscience modeling ...
Huiyu Yang+16 more
wiley +1 more source
Improved Mobility and Quality of Life Through Physical Activity Management in a Stroke Patient With Peripheral Arterial Disease: A Case Report. [PDF]
Maeno T, Matsumoto I, Harada K.
europepmc +1 more source
Serum magnesium level and arterial calcification in end-stage renal disease
H. Erik Meema+2 more
openalex +1 more source
Visualization of the Spiral Ganglion Neuron in Vivo Using a Novel 177Lu Nuclear Molecule Label
The study developed and validated a radionuclide‐labeled anti‐VGLUT1 antibody probe for the first nuclear imaging of cochlear spiral ganglion neurons (SGNs) in vivo. This approach may provide aid in screening candidates suitable for CI surgery by quantifying the number of surviving SGNs, and predicting the potential for postoperative hearing ...
Chenyang Kong+11 more
wiley +1 more source
Association of dietary vitamin E intake with peripheral arterial disease: A retrospective cross-sectional study. [PDF]
Liu Q+5 more
europepmc +1 more source