Results 61 to 70 of about 1,091,634 (307)

Diabetic Cardiovascular Disease Induced by Oxidative Stress. [PDF]

, 2015
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality among patients with diabetes mellitus (DM). DM can lead to multiple cardiovascular complications, including coronary artery disease (CAD), cardiac hypertrophy, and heart failure
Adam, Matti, Jagger, Ann, Kayama, Yosuke, Raaz, Uwe, Sakamoto, Masaya, Schellinger, Isabel N, Spin, Joshua M, Suzuki, Hirofumi, Toyama, Kensuke, Tsao, Philip S   +9 more
core   +2 more sources

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Prognostic Value of the Persistence or Change in Pericardial Effusion Status on Serial Echocardiograms in Pulmonary Arterial Hypertension [PDF]

, 2013
Background: Pericardial effusion in pulmonary arterial hypertension (PAH) is an indicator of right heart failure and a marker of poor prognosis; its significance on serial transthoracic echocardiograms (TTE) is not clear.
Dardari, Zeina A.
core  

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Accelerated Vascular Aging as a Possible Mechanism of Troponin I Release in the Absence of Clinically Manifested Myocardial Injury

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background We examined the association between clusters of vascular aging manifestations and ultrasensitivity cardiac troponin I in individuals without cardiovascular disease.
G. A. Alanis, P. Boutouyrie, M. Abouqateb, R. M. Bruno, M. Andrieu, B. Vedie, D. Geromin, N. Danchin, S. Laurent, X. Jouven, J. P. Empana   +10 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Coronary Artery Disease [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2020
Harsh, Agrawal, Ho-Hin K, Choy, Jason, Liu, Matthew, Auyoung, Michelle A, Albert   +4 more
openaire   +4 more sources

Ischemia-modified albumin in type 2 diabetic patients with and without peripheral arterial disease

Clinics, 2011
OBJECTIVE: To determine whether there is an association between serum ischemia-modified albumin and the risk factor profile in type 2 diabetic patients with peripheral arterial disease and to identify the risk markers for peripheral arterial disease ...
Shao-Gang Ma, Chun-Ling Wei, Bing Hong, Wei-Nan Yu   +3 more
doaj   +1 more source

Reduced RVSWI Is Associated With Increased Mortality in Connective Tissue Disease Associated Pulmonary Arterial Hypertension

Frontiers in Cardiovascular Medicine, 2020
Rationale: The prognosis of pulmonary arterial hypertension is poor, especially amongst patients with connective tissue disease related pulmonary arterial hypertension.
Katharine R. Clapham, Kristin B. Highland, Youlan Rao, Wassim H. Fares   +3 more
doaj   +1 more source

Circulating markers of arterial thrombosis and late-stage age-related macular degeneration: a case-control study.

, 2010
PURPOSE: The aim of this study was to examine the relation of late-stage age-related macular degeneration (AMD) with markers of systemic atherothrombosis. METHODS: A hospital-based case-control study of AMD was undertaken in London, UK.
A R Rudnicka, A Shankar, A von Clauss, AC Bird, AR Rudnicka, B Dasch, BG Armstrong, BL De Stavola, C Bunce, C Delcourt, CG Owen, DA Schaumberg, DA Schaumberg, DS Friedman, E Sato, Fibrinogen Studies Collaboration, G Chaine, G Malukiewicz-Wisniewska, GD Lowe, GJ Miller, H Hirvela, J Thornton, JA Cooper, JA Mares-Perlman, JJ Wang, JM Seddon, JM Seddon, JR Evans, JR Evans, JR Vingerling, KH Wu, L Hyman, N Cheung, N Congdon, P K MacCallum, PH Whincup, PK MacCallum, PL Lip, PT de Jong, R Klein, R Klein, R Klein, R Klein, R Klein, R Klein, R Klein, R Klein, R Klein, R Whitelocke, RD Sperduto, T Anderssen, T W Meade, The eye disease case-control study group, TW Meade, TY Wong, W Smith, W Smith, WG Christen, Y Duan, Y Tao   +59 more
core   +1 more source