Results 161 to 170 of about 391,153 (267)

The right time, the right cell: the potential for precision senotherapy in pulmonary arterial hypertension. [PDF]

Am J Physiol Lung Cell Mol Physiol
Hirsch K, Horn AG, Donato AJ, Schulze KM.   +3 more
europepmc   +1 more source

Development of a population pharmacokinetic model using combined paediatric and adult data for four pulmonary arterial hypertension drugs

British Journal of Clinical Pharmacology, EarlyView.
Aims Pulmonary arterial hypertension (PAH) is a syndrome characterized by elevated pulmonary artery pressure. We developed a population pharmacokinetic (PPK) model using combined plasma drug concentration data from Japanese paediatric (<15 years) and adult (≥15 years) patients with PAH to investigate the pharmacokinetic characteristics of PAH ...
Motoyasu Miura, Shimako Tanaka, Ririka Aihara, Shun Yamamoto, Yasumi Nakashima, Yasuharu Kashiwagura, Akio Hakamata, Sachiko Miyakawa, Mariko Tatsuguchi, Keiichi Odagiri, Noriyuki Namiki, Naoki Inui, Hiroshi Watanabe, Shinya Uchida   +13 more
wiley   +1 more source

Variation in <i>SNX29</i> and Acute Vasodilator Response in Pulmonary Arterial Hypertension. [PDF]

Circ Res
Karnes JH, Bao C, Liang S, Thayer T, Zagorski J, Naidu SR, West JD, Schwantes-An TH, Khajouei E, Banerjee K, Tiwari HK, Farol J, Martinez KL, Liu D, Ning Y, Sun Y, Jia Y, Wang J, Arora A, Batai K, Halliday SJ, Lutz K, Walsworth A, Frump AL, Rafikova O, Dai Z, Garcia JGN, Kim IM, Hemnes AR, Brittain E, Benza RL, Nichols WC, Chu A, Tang H, Desai AA.   +34 more
europepmc   +1 more source

Cardiovascular and neuropsychiatric outcomes with PCSK9 inhibitors in atherosclerotic cardiovascular disease: A retrospective cohort study

British Journal of Clinical Pharmacology, EarlyView.
Study design and main findings. After 1:1 propensity score matching, 60 885 PCSK9 inhibitor users and 60 885 statin‐only users with ASCVD were compared. Kaplan–Meier curves show 12‐month cumulative event‐free survival for MACE, psychiatric disease, and neurodegenerative disease.
Tianshu Gu, Yang Chen, Nan Zhang, Uazman Alam, Riccardo Proietti, Tong Liu, Kang‐Yin Chen, Gregory Y. H. Lip   +7 more
wiley   +1 more source

WCN25-4438 JC VIRUS IS UNDERESTIMATED IN KIDNEY TRANSPLANT RECIPIENTS

Kidney International Reports
Mirha Pjanic, Zrinka Bosnjak, Vesna Furic Cunko, Lea Katalinic, Ivana Juric, Mirna Aleckovic-Halilovic, Nikolina Basic-Jukic   +6 more
doaj   +1 more source

2025 Annual Review of Pulmonary Arterial Hypertension Clinical Research. [PDF]

Pulm Ther
Nascimento IAO, Souza R, Fernandes CJCDS.   +2 more
europepmc   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

Correction: Isolated Arterial Hypertension as a Rare Early Manifestation of Guillain-Barré Syndrome: A Case Report. [PDF]

Cureus
Hajjar EM, Kojmane W.
europepmc   +1 more source

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

BMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng, Yunfei Sha, Jiongyan Yang, Hongru Yang, Xiao Liang   +4 more
wiley   +1 more source

Experimental pulmonary arterial hypertension in mice with a pathogenic SOX17 variant. [PDF]

Sci Rep
Shinya Y, Hiraide T, Momoi M, Goto S, Katsumata Y, Inami T, Hakamata Y, Kataoka M, Ieda M.   +8 more
europepmc   +1 more source