Results 271 to 280 of about 710,185 (341)

Hemolysis Detected Following the Preparation and Collection of Blood in a Porcine Model Using a Syringe‐Based Aspiration Thrombectomy System for Autotransfusion

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Autologous transfusion of filtered, unwashed blood is a technique to mitigate the effects of blood loss during mechanical thrombectomy, but the degree of hemolysis resulting from this approach and guidance for blood return in this setting is not well understood.
Suhail Dohad, Mohammed M. Hoque, Jonathan H. Waters, Marc Salhanick   +3 more
wiley   +1 more source

Multiple Drug Intolerance Syndrome and Arterial Hypertension-Systematic Review and Meta-Analysis. [PDF]

J Clin Med
Rusinek J, Tyjas K, Ziółek W, Rajzer M, Stolarz-Skrzypek K.   +4 more
europepmc   +1 more source

Global, regional, and national trends in pulmonary arterial hypertension burden, 1990–2021: findings from the global burden of disease study 2021

Zhenhao Liu, Liumei Mo, Wenjing Cao, Kui Wang, Hua Gong, Li Chen, Wei Pan, Jin He   +7 more
openalex   +1 more source

Contemporary and Emerging Therapies in the Management of Refractory Angina: A Clinical Review

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Refractory angina (RA) represents a growing challenge in clinical cardiology, particularly in patients with obstructive coronary artery disease (CAD) who remain symptomatic despite optimal medical therapy and who are not candidates for revascularization.
Alex Angers‐Goulet, Siddhartha Mengi, David Garcia Labbé, Can Manh Nguyen, Jean‐Michel Paradis   +4 more
wiley   +1 more source

Gut Microbiome in Pulmonary Arterial Hypertension-An Emerging Frontier. [PDF]

Infect Dis Rep
Prisco SZ, Oliveira SD, Weir EK, Thenappan T, Al Ghouleh I.   +4 more
europepmc   +1 more source

Incidence and Predictors of Hypoattenuated Thickening and Device‐Related Thrombus at Three Months Postprocedural CT Assessment Following Left Atrial Appendage Occlusion With Amplatzer Devices—A Single‐Center Cohort

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Left atrial appendage occlusion (LAAO) has become a valuable alternative to long‐term anticoagulation for stroke prevention in patients with non‐valvular atrial fibrillation (AF), especially in those at high bleeding risk. Hypoattenuated thickening (HAT) and device‐related thrombus (DRT) remain notable postprocedural concerns ...
Pierre Guilleminot, Carole Richard, Antoine Roger, Marlène Daller, Gabriel Laurent, Catherine Vergely, Charles Guenancia, Thibaut Pommier   +7 more
wiley   +1 more source

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Ascending Doses and Dose Titration of Bexicaserin in Healthy Participants in a Randomized, Double‐Blind, Placebo‐Controlled Study

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Bexicaserin (LP352) is a selective superagonist of the 5‐hydroxytryptamine 2C (5‐HT2C) receptor currently in development for the treatment of seizures that arise from developmental and epileptic encephalopathies. This phase 1, double‐blind, placebo‐controlled multiple ascending dose (MAD) study assessed the safety, tolerability, and ...
Jonathan Williams, Rosa Chan, Chad Orevillo, Gale O'Connell, Dewey McLin, Shikha Polega, Nuggehally R. Srinivas, Randall Kaye   +7 more
wiley   +1 more source

Outcomes of Pulmonary Arterial Hypertension in Pregnancy: A Tertiary Care Retrospective Study. [PDF]

Cureus
Chopra S, Kaur A, Rai R, Sikka P, Aggarwal N, Suri V, Vijayvergiya R.   +6 more
europepmc   +1 more source

Single-Tablet Combination Therapy of Macitentan/Tadalafil for Patients with Pulmonary Arterial Hypertension: Qualitative Interview Study of the A DUE Phase 3 Trial [PDF]

Fenling Fan, Stacy N. Davis, Claire Burbridge, Kelly Chin, Michael Friberg, Ekkehard Grünig, Melanie Hughes, Pavel Jansa, Jörg Linder, Jennifer Rafalski, Armando A. Rodriguez, Jason A. Randall   +11 more
openalex   +1 more source

Impact of Antihypertensive Treatment on Outcomes of Adjuvant Bevacizumab for Ovarian Cancer (IATRO), Results from a Nationwide Emulated Clinical Trial

Clinical Pharmacology &Therapeutics, EarlyView.
Antiangiogenic therapy with bevacizumab improves outcomes in ovarian cancer but induces hypertension, leading to major adverse cardiovascular events (MACE). While calcium channel blockers (CCBs) and angiotensin‐converting enzyme inhibitors (ACEi) are recommended for managing bevacizumab‐associated hypertension, their impacts on cancer progression and ...
Floriane Jochum, Élise Dumas, Joe‐Elie Salem, Stéphane Ederhy, Anne‐Sophie Hamy, Lise Lecointre, Enora Laas, Fabien Reyal, Fabrice Lecuru, Cherif Akladios, Paul Gougis   +10 more
wiley   +1 more source