Results 21 to 30 of about 672,953 (296)

The molecular genetics and cellular mechanisms underlying pulmonary arterial hypertension [PDF]

open access: yes, 2012
Pulmonary arterial hypertension (PAH) is an incurable disorder clinically characterised by a sustained elevation of mean arterial pressure in the absence of systemic involvement.
Machado, Rajiv
core   +2 more sources

Arterial Hypertension and Risk of Mortality in Patients with COVID-19 Infection

open access: yesSoutheastern European Medical Journal, 2022
COVID-19 is currently a major global health concern. Among many unanswered questions related to COVID-19, some of the most debated ones are those concerning arterial hypertension.
Nikolina Bukal   +8 more
doaj   +1 more source

Microvascular alterations in hypertension and vascular aging [PDF]

open access: yes, 2017
Hypertension and aging are characterized by vascular remodelling and stiffness as well as endothelial dysfunction. Endothelial function declines with age, since aging is associated with senescence of the endothelium due to increased rate of apoptosis and
Battistoni, Allegra   +5 more
core   +1 more source

Influence of the new immunosuppressive combinations on arterial hypertension after renal transplantation [PDF]

open access: yes, 1932
Influence of the new immunosuppressive combinations on arterial hypertension after renal transplantation. Arterial hypertension is highly prevalent after renal transplantation and may contribute to the risk of cardiovascular disease.
Morales, José M.
core   +1 more source

Irisin and Cardiometabolic Disorders in Obesity: A Systematic Review

open access: yesInternational Journal of Inflammation, 2023
Background. Overweight and obesity are global health issues, impacting a significant portion of young adults. Obesity is a complex condition influenced by genetics and environmental factors, leading to increased susceptibility to cardiovascular diseases (
Jorge da Silva Pinho-Jr   +6 more
doaj   +1 more source

Residual risk identified in routine noninvasive follow-up assessments in pulmonary arterial hypertension

open access: yesERJ Open Research, 2023
Background The 2022 ESC/ERS guidelines on pulmonary hypertension recommend noninvasive risk assessments based on three clinical variables during follow-up in patients with pulmonary arterial hypertension (PAH).
Jonna Ostermann   +6 more
doaj   +1 more source

Impaired endothelial function of the retinal vasculature in hypertensive patients [PDF]

open access: yes, 2004
<p><b>Background and Purpose:</b> Arterial hypertension constitutes a central factor in the pathogenesis of stroke. We examined endothelial function of the retinal vasculature as a model of the cerebral circulation.</p> <p ...
Delles, C.   +5 more
core   +1 more source

Transcription factors in the pathogenesis of pulmonary arterial hypertension—Current knowledge and therapeutic potential

open access: yesFrontiers in Cardiovascular Medicine, 2023
Pulmonary arterial hypertension (PAH) is a disease characterized by elevated pulmonary vascular resistance and pulmonary artery pressure. Mortality remains high in severe cases despite significant advances in management and pharmacotherapy.
Jakob Körbelin   +10 more
doaj   +1 more source

The role of endothelin-1 in pulmonary arterial hypertension. [PDF]

open access: yes, 2014
Pulmonary arterial hypertension (PAH) is a rare but debilitating disease, which if left untreated rapidly progresses to right ventricular failure and eventually death. In the quest to understand the pathogenesis of this disease differences in the profile,
Chester, AH, Yacoub, MH
core   +1 more source

Novel signaling pathways in pulmonary arterial hypertension (2015 Grover Conference Series) [PDF]

open access: yes, 2016
The proliferative endothelial and smooth muscle cell phenotype, inflammation, and pulmonary vascular remodeling are prominent features of pulmonary arterial hypertension (PAH).
Awad, Keytam S.   +3 more
core   +1 more source

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