The role of the right ventricle in pulmonary arterial hypertension [PDF]
Although changes in the pulmonary vasculature are the primary cause of pulmonary arterial hypertension (PAH), severity of symptoms and survival are strongly associated with right ventricular function, and right heart failure is the main cause of death in
A. Vonk Noordegraaf +3 more
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CXCR4 Inhibition Ameliorates Severe Obliterative Pulmonary Hypertension and Accumulation of C-Kit+ Cells in Rats [PDF]
Successful curative treatment of severe pulmonary arterial hypertension with luminal obliteration will require a thorough understanding of the mechanism underlying the development and progression of pulmonary vascular lesions.
Alhussini, Aysar A. +35 more
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The study aims to evaluate the long‐term incidence of cardiovascular events (CVE) and compare the effectiveness of medical and surgical interventions using a combined cardiovascular endpoint in individuals diagnosed with primary aldosteronism (PA).
Sofia Benameur +9 more
doaj +1 more source
Hipertensão arterial na gravidez: avaliação de um protocolo de tratamento Arterial hypertension in pregnancy: analysis of a manegement protocol [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina. Centro de Ciências da Saúde. Programa de Pós-Graduação em Ciências Médicas.Introdução: A hipertensão arterial é a mais importante causa de morte materna no estado de Santa Catarina e nos ...
Jorge Abi Saab Neto +1 more
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Pulmonary arterial hypertension: diagnosis and treatment
Pulmonary arterial hypertension is one of the clinical groups of arterial hypertension. It is a rare, chronic disease with a very poor prognosis.
Agnieszka Łętek +4 more
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Right heart adaptation to pulmonary arterial hypertension: physiology and pathobiology. [PDF]
Survival in patients with pulmonary arterial hypertension (PAH) is closely related to right ventricular (RV) function. Although pulmonary load is an important determinant of RV systolic function in PAH, there remains a significant variability in RV ...
Voelkel, N.F. +32 more
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Hypertension is a rapidly moving clinical field with frequent developments in new pharmacologic agents and management strategies. Perhaps more importantly, there have been substantial improvements in our understanding of how best to use the drugs ...
Farrugia, Emanuel
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Monotherapy versus dual therapy for the initial treatment of hypertension (PATHWAY-1):a randomised double-blind controlled trial [PDF]
INTRODUCTION: Previous studies have suggested that more intensive initial therapy for hypertension results in better long-term blood pressure (BP) control.
Williams, B +28 more
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Cardiovascular regulation and vascular structure in prehypertension and coronary heart disease [PDF]
The aim of this thesis was to characterize vascular structure and different aspects of cardiovascular regulation in otherwise healthy subjects with slightly elevated blood pressure and compare to healthy subjects with normotension and also investigate ...
Myredal, Anna
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Tadalafil therapy for pulmonary arterial hypertension
BACKGROUND: Treatment options for pulmonary arterial hypertension target the prostacyclin, endothelin, or nitric oxide pathways. Tadalafil, a phosphodiesterase type-5 inhibitor, increases cGMP, the final mediator in the nitric oxide pathway.
Frumkin, L. +26 more
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