Results 131 to 140 of about 491,319 (340)

Insights on Advances in 3D Bioprinting for Peripheral Nerve Regeneration

open access: yesAdvanced Therapeutics, EarlyView.
Peripheral nerve injury is a common condition due to trauma that significantly impacts the life of the affected individual. This review explores the anatomy, classification, and pathophysiology of peripheral nerve injuries. It also discusses various types of nerve conduits and presents a detailed review of 3D bioprinted nerve conduits used in both in ...
Nasera Rizwana   +5 more
wiley   +1 more source

Dynamics of information loadings at school and psychofunctional development of children of the capital megalopolis

open access: yesRUDN Journal of Ecology and Life Safety, 2012
In article there are studying of dynamics of information loadings in school and level of psycho-functional development of children of the capital megalopolis are given.
V A Nazarov   +2 more
doaj  

Viral‐Mediated Connexin 26 Expression Combined with Dexamethasone Rescues Hearing in a Conditional Gjb2 Null Mice Model

open access: yesAdvanced Science, EarlyView.
AAV2.7m8 serotype combined with the gfaABC1D promoter targets infection of supporting cells (SCs). AAV2.7m8‐gfaABC1D‐Gjb2 administration to mice results in excessive immune responses. The combination of AAV2.7m8‐gfaABC1D‐Gjb2 with dexamethasone (DEX) shows a synergistic effect and enhances the gene therapy effect in a conditional Cx26 null mice model ...
Xiaohui Wang   +8 more
wiley   +1 more source

Single Administration of AAV‐mAtp6v1b2 Gene Therapy Rescues Hearing and Vestibular Disorders Caused by Atp6v1b2‐Induced Lysosomal Dysfunction in Hair Cells

open access: yesAdvanced Science, EarlyView.
Wei et al. establish a hair cell‐specific conditional knockout mouse model (Atp6v1b2fl/fl;Atoh1Cre/+), and demonstrate the importance of Atp6v1b2 for hair cell through maintaining the survival of lysosomes. A single administration of AAV‐ie‐Eh3‐mAtp6v1b2 through scala media at P0‐P2 realizes function compensation and restores hearing and balance ...
Gege Wei   +15 more
wiley   +1 more source

Transcriptomic Profiling Unveils EDN3+ Meningeal Fibroblasts as Key Players in Sturge‐Weber Syndrome Pathogenesis

open access: yesAdvanced Science, EarlyView.
Sturge‐Weber syndrome (SWS) is characterized by leptomeningeal vascular malformations, leading to seizures and stroke. Analysis of 119 446 brain cells from SWS patients uncovered distinct cell heterogeneity and identified an EDN3⁺ meningeal fibroblast cluster, with WNT5A emerging as a potential key driver of SWS progression and a promising therapeutic ...
Daosheng Ai   +14 more
wiley   +1 more source

A 3D-Printed Piezoelectric Microdevice for Human Energy Harvesting for Wearable Biosensors

open access: yesMicromachines
The human body is a source of multiple types of energy, such as mechanical, thermal and biochemical, which can be scavenged through appropriate technological means.
Ihor Sobianin   +2 more
doaj   +1 more source

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