Results 161 to 170 of about 491,319 (340)

A prospective randomized controlled study on the role of restoring liver diaphragm surface tension and pain control at port sites in optimizing pain management following laparoscopic cholecystectomy

open access: yesAnnals of Gastroenterological Surgery, Volume 7, Issue 1, Page 131-137, January 2023., 2023
The cornerstone of treatment for symptomatic gallbladder stones is laparoscopic cholecystectomy. Pain is the commonest cause of extended hospital stay. Disturbance of liver—diaphragm surface tension is the main cause of pain. Retained CO2 is a major concern post laparoscopic cholecystectomy.
Mohamed Lotfy Ali Abuelzein   +3 more
wiley   +1 more source

Berberine is a Novel Mitochondrial Calcium Uniporter Inhibitor that Disrupts MCU‐EMRE Assembly

open access: yesAdvanced Science, EarlyView.
Berberine, a safe and FDA‐approved drug, is identified as a novel mitochondrial calcium uniporter (MCU) inhibitor. By disrupting MCU‐EMRE interaction, Berberine prevents mitochondrial calcium overload and protects against ischemia/reperfusion injury, offering a promising therapeutic strategy for diseases linked to mitochondrial calcium dysregulation ...
Haixin Zhao   +17 more
wiley   +1 more source

Treatment strategies for unruptured pancreaticoduodenal artery aneurysms associated with celiac artery occlusion

open access: yesAnnals of Gastroenterological Surgery, Volume 7, Issue 1, Page 182-189, January 2023., 2023
Since celiac artery occlusion represents a common attributable aetiology for these aneurysms, restoration of blood flow to the regions supplied by the celiac artery should also be taken into account when designing a treatment plan. Here, we present 4 cases of PDA aneurysms coexisting with coeliac artery occlusion, all of which were managed with bypass ...
Koji Kubota   +4 more
wiley   +1 more source

The Cerebrospinal Fluid Secretion Rate Increases in Awake and Freely Moving Rats but Differs With Experimental Methodology

open access: yesAdvanced Science, EarlyView.
CSF dynamics are vital for neurological health. Yet accurate quantification of CSF rates is challenging. Using a novel technique in awake, freely moving rats, significantly higher secretion rates are found than in anesthetized rats. The findings highlight the importance of awake models and the adaptability of methods for studying CSF changes influenced
Trine L. Toft‐Bertelsen   +6 more
wiley   +1 more source

Mean arterial pressure in critically ill adults receiving vasopressors: A multicentre, observational study. [PDF]

open access: yesCrit Care Resusc
White KC   +18 more
europepmc   +1 more source

Arterial Pressure Responses to Discontinuing Antihypertensive Drugs [PDF]

open access: bronze, 1968
Harriet P. Dustan   +3 more
openalex   +1 more source

DNA‐PKcs‐Driven YAP1 Phosphorylation and Nuclear Translocation: a Key Regulator of Ferroptosis in Hyperglycemia‐Induced Cardiac Dysfunction in Type 1 Diabetes

open access: yesAdvanced Science, EarlyView.
In the context of chronic hyperglycemia, a DDR is initiated, leading to the pathological activation of DNA‐PKcs in the diabetic heart. This activated DNA‐PKcs directly interacts with and phosphorylates YAP1 at Thr226, thereby increasing the nuclear expression of YAP1.
Junyan Wang   +10 more
wiley   +1 more source

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