Results 41 to 50 of about 13,431 (262)

Thalamo‐Lesional Connectivity Signatures of Bilateral Tonic–Clonic Seizures in Focal Cortical Dysplasia‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie, Xiaotong Li, Venkata Sita Priyanka Illapani, Leigh N. Sepeta, Jason Schroeder, Chima O. Oluigbo, Madison M. Berl, William D. Gaillard, Nathan T. Cohen   +8 more
wiley   +1 more source

Arterial spin labeling versus 18F-FDG-PET to identify mild cognitive impairment

NeuroImage: Clinical, 2020
Neurodegenerative biomarkers support diagnosis and measurement of disease progression in the Alzheimer's disease (AD) continuum. 18F-Fluorodeoxyglucose Positron Emission Tomography (18F-FDG-PET), which measures glucose metabolism, is one of the most ...
Sudipto Dolui, Zhengjun Li, Ilya M. Nasrallah, John A. Detre, David A. Wolk   +4 more
doaj   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Noninvasive in vivo assessment of placental insufficiency using pCASL: a prospective case–control study

The Egyptian Journal of Radiology and Nuclear Medicine
Background Arterial spin labeling is a noninvasive imaging modality that does not use contrast for evaluation of placental perfusion in the placental pathological conditions.
Ghada Awad, Alaa Mohamed Reda, Rasha Lotfy Younis, Manal Mostafa Hassan, Rania Essam Eldin Mohamed Ali   +4 more
doaj   +1 more source

Engineered Microvascular Model of the Blood–Brain–Tumor Barrier Reveals Endothelial Remodeling in Diffuse Midline Glioma

Advanced Healthcare Materials, EarlyView.
We developed a patient‐derived, functional microfluidic model of the diffuse midline glioma (DMG) blood–brain–tumor barrier (BBTB) comprised of endothelial cells, astrocytes, pericytes, and tumor cells. The system forms perfusable microvasculature, reveals the BBTB retains vascular integrity, identifies DMG‐specific transcriptomic changes distinct from
Kimberly R. Bennett, Yann S. Vanrobaeys, Tessy Teboh, Zakiya Smith, Anderson Scott, Cynthia Hajal, Paula T. Hammond, Joelle P. Straehla   +7 more
wiley   +1 more source

Angiografía no contrastada con "Arterial Spin Labeling"

Revista Chilena de Radiología
Introducción: La angiografía por resonancia magnética no contrastada realizada con "Arterial Spin Labeling" (ARM ASL) es un método diseñado para marcar los espines sanguíneos y así crear un contraste endógeno adecuado para evaluar territorios vasculares ...
Jorge Delgado, Simón Rascovsky, Victor Calvo, Fredy López, Bernd Foerster, Gabriel Castrillón   +5 more
doaj   +1 more source

The NIMH intramural healthy volunteer dataset: A comprehensive MEG, MRI, and behavioral resource

Scientific Data, 2022
Measurement(s) brain activity • Blood Oxygen Level-Dependent Functional MRI • regional part of brain • cerebral white matter structure • cerebral blood flow Technology Type(s) Magnetoencephalography • Functional Magnetic Resonance Imaging • Magnetic ...
Allison C. Nugent, Adam G. Thomas, Margaret Mahoney, Alison Gibbons, Jarrod T. Smith, Antoinette J. Charles, Jacob S. Shaw, Jeffrey D. Stout, Anna M. Namyst, Arshitha Basavaraj, Eric Earl, Travis Riddle, Joseph Snow, Shruti Japee, Adriana J. Pavletic, Stephen Sinclair, Vinai Roopchansingh, Peter A. Bandettini, Joyce Chung   +18 more
doaj   +1 more source

Spatially‐confined arterial spin‐labeling with FAIR [PDF]

Journal of Magnetic Resonance Imaging, 2005
AbstractPurposeTo investigate the effectiveness of slab‐selective inversion in pulsed arterial spin labeling with body coil excitation as a means to reduce large vessel contamination of the perfusion signal.Materials and MethodsStudies were conducted by varying the tagging width in multislice flow‐sensitive alternating inversion recovery (FAIR) in ...
Yan, Zhang, Hee Kwon, Song, Jiongjiong, Wang, Aranee, Techawiboonwong, Felix W, Wehrli   +4 more
openaire   +2 more sources

Arterial Spin-Labeling Perfusion for PHACE Syndrome [PDF]

American Journal of Neuroradiology, 2020
Arterial stroke is a rare-but-reported complication in patients with posterior fossa brain malformations, hemangiomas, arterial anomalies, coarctation of the aorta and cardiac defects, and eye abnormalities (PHACE) syndrome. Currently, stroke risk is inferred by the severity of arterial anomalies identified on MRA, though no evidenced-based data exist.
M.D. Mamlouk, A. Vossough, L. Caschera, M. Maheshwari, C.P. Hess   +4 more
openaire   +4 more sources

Flexible Dielectric Acoustic Resonator Patch for Tissue Regeneration

Advanced Materials, EarlyView.
A flexible dielectric acoustic resonator patch enables MHz‐range ultrasound generation through resonance amplification without using piezoelectric materials. Conformal integration on a curved substrate allows efficient acoustic delivery to tissue‐mimicking environments.
Donyoung Kang, Byeongseok Ryu, Sujeong Ahn, Junhyub Kim, Myeonghun Jang, Jeong Ho Cho, Won‐Gun Koh, Hyungsuk Lee   +7 more
wiley   +1 more source