Results 191 to 200 of about 1,290,229 (402)

Arterial Stiffness and Coronary Artery Disease

open access: yesEMJ Cardiology, 2016
Although there have been marked improvements in both diagnostic and therapeutic interventions over several decades, coronary artery disease (CAD) remains the leading cause of death worldwide. Intensive modification of classic risk factors such as hypertension, diabetes mellitus, dyslipidaemia, and cigarette smoking has significantly reduced the ...
openaire   +2 more sources

Reversal of Stress‐Induced PIEZO1 Elevation with Mechanically Adapted Epicardial Patch for Myocardial Infarction Treatment

open access: yesAdvanced Science, EarlyView.
This work identifies fine‐tuning the expression of PIEZO1 as a critical molecular mechanism underlying the treatment of myocardial infarction by mechanically adapted cardiac patches, which can support the clinical translation of cardiac patch devices.
Yuwen Lu   +18 more
wiley   +1 more source

Circulating TREM2 as a noninvasive diagnostic biomarker for NASH in patients with elevated liver stiffness

open access: yesHepatology, EarlyView., 2022
Abstract Background and Aims Reliable noninvasive biomarkers are an unmet clinical need for the diagnosis of NASH. This study investigates the diagnostic accuracy of the circulating triggering receptor expressed on myeloid cells 2 (plasma TREM2) as a biomarker for NASH in patients with NAFLD and elevated liver stiffness.
Vineesh Indira Chandran   +17 more
wiley   +1 more source

Clinical applications of arterial stiffness: therapeutics and pharmacology [PDF]

open access: bronze, 2002
Stéphane Laurent   +4 more
openalex   +1 more source

A Touch Enabled Hemodynamic and Metabolic Monitor

open access: yesAdvanced Science, EarlyView.
This work presents a touch‐based hybrid platform for simultaneous monitoring of vital signs and sweat metabolites. With a simple tri‐finger touch of 4–6 min, users can concurrently get to know their glucose, uric acid, cortisol levels from fingertip sweat, along with blood pressure and heart rate.
Omeed Djassemi   +19 more
wiley   +1 more source

CD11b+CD43hiLy6Clo splenocyte‐derived macrophages exacerbate liver fibrosis via spleen–liver axis

open access: yesHepatology, EarlyView., 2022
A population of splenic monocytes migrate into the liver and shift to macrophages, which account for the exacerbation of liver fibrosis. Abstract Background and Aims Monocyte‐derived macrophages (MoMFs), a dominant population of hepatic macrophages under inflammation, play a crucial role in liver fibrosis progression.
Shaoying Zhang   +18 more
wiley   +1 more source

The effects of thyrotoxicosis and its treatment on central arterial stiffness [PDF]

open access: bronze, 2002
Kofi Obuobie   +4 more
openalex   +1 more source

A Human Engineered Heart Tissue‐Derived Lipotoxic Diabetic Cardiomyopathy Model Revealed Early Benefits of Empagliflozin

open access: yesAdvanced Science, EarlyView.
This study develops a human engineered heart tissue‐derived model of diabetic cardiomyopathy that accurately replicates the dynamic changes in the structural, contractile, and electrophysiological properties of the myocardium. Furthermore, this model is used to confirm the direct protective effects of empagliflozin on the heart through an SGLT2 off ...
Lin Cai   +9 more
wiley   +1 more source

Implantable Biophotonic Device for Wirelessly Cancer Real‐Time Monitoring and Modulable Treatment

open access: yesAdvanced Science, EarlyView.
A wirelessly implantable biophotonic device is capable of distinguishing tumors and evaluating their progression by monitoring sO2 levels indicative of the tumor hypoxic microenvironment. Additionally, this device is not only employed for in situ PDT but also for concurrent monitoring of chemotherapy and PDT progress, thereby enabling the evaluation ...
Renhao Nie   +8 more
wiley   +1 more source

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