Results 71 to 80 of about 143,170 (303)

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Correlation between the triglyceride-glucose index and arterial stiffness in Japanese individuals with normoglycaemia: a cross-sectional study

BMC Endocrine Disorders
Background The association between the triglyceride-glucose (TyG) index and arterial stiffness in individuals with normoglycaemia remains unclear. We aimed to evaluate the relationship between the TyG index and arterial stiffness in Japanese individuals ...
Yuying Cai, Wenyue Sha, Hailian Deng, Tuming Zhang, Linlin Yang, Yueying Wu, Jinhua Luo, Guangyan Liu, Yu Yang, Dehui Feng   +9 more
doaj   +1 more source

Hypertension and arterial stiffness in heart transplantation patients

Clinics
OBJECTIVES: Post-transplantation hypertension is prevalent and is associated with increased cardiovascular morbidity and subsequent graft dysfunction. The present study aimed to identify the factors associated with arterial stiffness as measured by the ...
João David de Souza-Neto, ĺtalo Martins de Oliveira, Hermano Alexandre Lima-Rocha, José Wellington Oliveira-Lima, Fernando Bacal   +4 more
doaj   +1 more source

PO-23 A SYSTEMATIC REVIEW ON THE EFFECT OF ACUTE AEROBIC EXERCISE ON ARTERIAL STIFFNESS REVEALS A DIFFERENTIAL RESPONSE IN THE UPPER AND LOWER ARTERIAL SEGMENTS

Artery Research, 2016
Objectives: The overall impact of resistance-type exercises and chronic physical activity on the modulation of arterial stiffness has been well characterized; however, the impact of acute aerobic exercise remains unclear.
Alexandra B. Cooke, Andrew F. Mutter, Oliver Saleh, Yessica-Haydee Gomez, Stella S. Daskalopoulou   +4 more
doaj   +1 more source

Association between fibrinogen/albumin ratio and arterial stiffness in patients with type 2 diabetes: A cross-sectional study

Frontiers in Pharmacology, 2023
Background: Fibrinogen albumin ratio (FAR) is significantly correlated with the severity and prognosis of cardiovascular disease (CVD). Arterial stiffness is an early lesion of CVD, but no studies have examined the correlation between arterial stiffness ...
Chun-mei Chen, Chun-feng Lu, Wang-shu Liu, Zhen-hua Gong, Xue-qin Wang, Feng Xu, Jian-feng Ji, Xing-xing Fang   +7 more
doaj   +1 more source

Influence of age, risk factors, and cardiovascular and renal disease on arterial stiffness: clinical applications [PDF]

, 2017
Age is the main clinical determinant of large artery stiffness. Central arteries stiffen progressively with age, whereas peripheral muscular arteries change little with age.
Asmar, Roland, Benetos, Athanase, Izzo, Joseph, Mitchell, Gary, Resnick, Lawrence, Safar, Michel, Waeber, Bernard   +6 more
core  

Diabetic Cardiovascular Disease Induced by Oxidative Stress. [PDF]

, 2015
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality among patients with diabetes mellitus (DM). DM can lead to multiple cardiovascular complications, including coronary artery disease (CAD), cardiac hypertrophy, and heart failure
Adam, Matti, Jagger, Ann, Kayama, Yosuke, Raaz, Uwe, Sakamoto, Masaya, Schellinger, Isabel N, Spin, Joshua M, Suzuki, Hirofumi, Toyama, Kensuke, Tsao, Philip S   +9 more
core   +2 more sources

Microengineered Gradient Hydrogels for Mechanobiology

Advanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong, Deepu Ashok, Anna Waterhouse, Marcela M. M. Bilek, Daniele Vigolo   +4 more
wiley   +1 more source

Association of C2, a derivative of the radial artery pressure waveform, with new onset of type 2 diabetes mellitus: the MESA study. [PDF]

, 2019
BackgroundAlthough microvascular dysfunction is known to result from diabetes, it might also lead to diabetes. Lower values of C2, a derivative of the radial artery pressure waveform, indicate microvascular dysfunction and predict hypertension and ...
Allison, Matthew A, Duprez, Daniel A, Forbang, Nkete I, Jacobs, David R, Peralta, Carmen A, Shea, Steven   +5 more
core   +3 more sources

Arterial stiffness and coronary artery disease

Current Opinion in Cardiology, 2015
The current traditional risk scores are not sufficient to predict the full incidence of cardiovascular disease. In this brief review, we discuss the pathophysiological mechanisms through which arterial stiffness affects cardiac function and the additive value of markers of arterial stiffness, to detect the presence of coronary artery disease (CAD) and ...
Ikonomidis, Ignatios, Makavos, George, Lekakis, John   +2 more
openaire   +3 more sources